Detailed information NTG0352746

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: GOM48_RS09075
• Genome accession: NZ_CP046523
• Coordinates: 1795141..1797675 (-)
• Length: 844 a.a.
• NCBI ID: WP_235097422.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain SOD
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1790141..1802675

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOM48_RS09050 (GOM48_08985)	ruvA	1790647..1791240 (-)	594	WP_084925449.1	Holliday junction branch migration protein RuvA	Machinery gene
GOM48_RS09055 (GOM48_08990)	-	1791399..1791896 (+)	498	WP_235098764.1	helix-turn-helix domain-containing protein	-
GOM48_RS09060 (GOM48_08995)	hexB	1792045..1793994 (-)	1950	WP_235097416.1	DNA mismatch repair endonuclease MutL	Machinery gene
GOM48_RS09065 (GOM48_09000)	-	1794203..1794643 (+)	441	WP_235097418.1	LytTR family DNA-binding domain-containing protein	-
GOM48_RS09070 (GOM48_09005)	-	1794640..1795098 (+)	459	WP_235097420.1	DUF3021 domain-containing protein	-
GOM48_RS09075 (GOM48_09010)	hexA	1795141..1797675 (-)	2535	WP_235097422.1	DNA mismatch repair protein MutS	Machinery gene
GOM48_RS09080 (GOM48_09015)	argR	1797726..1798172 (-)	447	WP_061418468.1	arginine repressor	-
GOM48_RS09085 (GOM48_09020)	argS	1798320..1800008 (+)	1689	WP_235097425.1	arginine--tRNA ligase	-
GOM48_RS09090 (GOM48_09025)	-	1800296..1800541 (+)	246	WP_132972795.1	MarR family transcriptional regulator	-
GOM48_RS09095 (GOM48_09030)	-	1800737..1801999 (+)	1263	WP_235097426.1	NRAMP family divalent metal transporter	-
GOM48_RS09100 (GOM48_09035)	nrdI	1802084..1802554 (-)	471	WP_235097428.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-

Sequence

Protein

• Length: 844 a.a.
• Molecular weight: 94708.11 Da
• Isoelectric Point: 4.8297

>NTDB_id=352746 GOM48_RS09075 WP_235097422.1 1795141..1797675(-) (hexA) [Streptococcus oralis strain SOD]
MTTEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAAQILEISLTSRNKNAENPIPMAGVPYHSAQQYIDVLI
EQGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVAIDRDGNQFGLAYMDLVTGDFYVTGLLDFTL
VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKEGFEDIHLLDQRLAAVEQAAASKLLQYVHRTQMRELNHLKP
VIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLFWLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFF
ERSDLTDSLKGVYDIERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELESLISAAIAP
EAPHVITEGGIIRTGFDETLDKYRRVLREGTSWIAEIEAKERENSGISTLKIDYNKKDGYYFHVTNSQLGNVPAHFFRKA
TLKNSERFGTEELARIEGDMLEAREKSANLEYEIFMRIREEVSKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFG
DDSQIDIQKGRHAVVEKVMGAQTYIPNSIQMSEDTSIQLITGPNMSGKSTYMRQLAMMAVMAQLGSYVPAESAHLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDELGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHEL
TSLESSLEHLVNVHVATLEQDGQVTFLHKIEPGPADKSYGIHVAKIAGLPAELLARADKILAQLESQGTESPAPMRQTSA
VTEQMSLFDAPEEHPILAELAELDVYNMTPMQAMNVLVELKQKL

Nucleotide

• Length: 2535 bp

>NTDB_id=352746 GOM48_RS09075 WP_235097422.1 1795141..1797675(-) (hexA) [Streptococcus oralis strain SOD]
ATGACGACAGAAAAACTATCACCTGGTATGCAGCAGTATGTGGATATTAAAAAGCAATATCCAGATGCTTTTTTGCTCTT
TCGGATGGGTGATTTTTATGAGCTGTTTTATGAAGATGCGGTCAATGCGGCGCAGATTTTAGAGATTTCACTGACCAGTC
GTAATAAAAATGCAGAAAATCCGATACCCATGGCTGGTGTTCCCTATCATTCTGCCCAGCAGTATATCGATGTTTTGATT
GAGCAGGGCTATAAGGTGGCTATTGCCGAGCAGATGGAAGACCCTAAACAAGCGGTTGGGGTTGTCAAGCGAGAGGTGGT
TCAGGTCATCACCCCCGGTACAGTGGTTGATAGTAGTAAGCCCGATAGTCAGAACAATTTCTTGGTTGCCATAGATCGTG
ATGGCAATCAGTTTGGTCTGGCATATATGGATCTGGTGACGGGTGACTTTTATGTGACAGGTTTATTGGATTTCACGCTG
GTTTGTGGGGAAATCCGTAACCTCAAGGCTCGTGAAGTGGTGCTGGGTTATGATTTGTCTGAGGAAGAAGAACAAATCCT
CAGCCGTCAGATGAATTTGGTGCTTTCCTATGAGAAGGAAGGCTTTGAGGATATTCATTTACTGGATCAACGACTGGCAG
CTGTGGAGCAAGCAGCAGCTAGTAAGCTCCTCCAGTATGTTCACCGTACCCAGATGCGGGAATTGAATCATCTCAAACCA
GTTATCCGCTATGAAATCAAAGATTTCTTACAGATGGACTATGCGACAAAGGCTAGTCTGGATTTGGTTGAGAATGCTCG
TTCCGGCAAGAAGCAAGGCAGTCTTTTCTGGCTTTTGGATGAAACCAAAACAGCTATGGGTATGCGACTCTTGCGTTCTT
GGATCCATCGTCCTTTGATTGACAAGGAGCGAATCGTCCAACGTCAAGAGGTGGTGCAGGTCTTTCTTGACCACTTCTTT
GAGCGCAGTGATTTGACAGACAGTCTCAAGGGTGTTTATGACATCGAACGCTTGGCTAGTCGGGTTTCTTTTGGCAAGAC
CAATCCCAAGGATCTCTTGCAACTGGCGACTACCTTATCTAGTGTGCCACGGATTCGAGCGATTTTAGAGGGAATGGAGC
AGCCTGCTTTAGCTTATCTCATCGCACAGTTGGATGCCATTCCAGAGTTAGAGAGTTTGATTAGCGCAGCGATAGCCCCT
GAAGCTCCTCATGTGATTACGGAAGGTGGCATTATCCGTACGGGATTTGATGAGACCTTGGATAAATACCGTCGTGTGCT
CAGAGAAGGGACTAGCTGGATTGCTGAGATTGAGGCTAAGGAGCGAGAAAACTCTGGCATCAGCACGCTCAAGATTGACT
ACAATAAAAAGGATGGCTACTACTTCCATGTGACCAATTCGCAACTGGGAAATGTGCCAGCCCACTTTTTCCGAAAGGCG
ACGCTGAAAAACTCAGAACGCTTTGGTACCGAAGAATTAGCCCGTATCGAGGGAGATATGCTGGAGGCGCGTGAGAAGTC
AGCCAACCTAGAATATGAAATCTTTATGCGTATCCGTGAGGAAGTCAGCAAGTACATCCAGCGTTTGCAGGCTTTAGCCC
AAGGAATTGCGACGGTTGATGTCTTGCAAAGTCTCGCAGTTGTGGCTGAAACACAGCATTTGATTCGACCTGAGTTTGGA
GACGATTCACAAATTGATATCCAGAAAGGGCGCCATGCTGTCGTTGAAAAGGTCATGGGAGCGCAGACCTACATTCCAAA
CAGTATCCAGATGTCAGAAGATACCAGCATTCAACTGATCACGGGACCCAACATGAGCGGGAAGTCCACCTATATGCGCC
AACTAGCCATGATGGCGGTTATGGCCCAGCTAGGCTCGTATGTGCCGGCAGAGAGTGCCCATTTGCCTATCTTCGATGCT
ATCTTTACCCGTATCGGAGCAGCAGATGACTTGGTTTCAGGTCAATCAACCTTTATGGTGGAGATGATGGAGGCCAACAA
TGCCATTTCGCATGCGACCAAGAATTCCTTGATTCTCTTTGATGAATTGGGACGCGGAACTGCAACTTATGACGGGATGG
CTCTTGCCCAGTCCATCATCGAATACATTCATGAACATATCGGAGCCAAAACCCTCTTTGCGACCCACTATCATGAGTTG
ACTAGTCTGGAGTCCAGTTTGGAACACTTGGTCAATGTCCACGTGGCAACCTTGGAGCAGGATGGGCAGGTCACCTTCCT
TCACAAGATCGAACCAGGACCAGCTGACAAATCCTATGGTATCCACGTTGCTAAGATTGCTGGTTTACCGGCAGAACTTT
TAGCAAGGGCAGATAAGATTTTGGCTCAGTTAGAGAGTCAGGGTACAGAAAGTCCAGCTCCGATGAGACAAACAAGTGCT
GTTACAGAGCAGATGTCACTCTTTGACGCGCCTGAAGAGCATCCTATCCTAGCAGAATTAGCAGAACTGGATGTATACAA
TATGACACCTATGCAGGCTATGAATGTCTTAGTTGAGCTTAAACAAAAGTTATAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

• MutS domain III (MutS_III) (256-546)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	96.445	100	0.964
mutS	Pseudomonas stutzeri strain ATCC 17587	37.106	100	0.377