Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   GOM48_RS09060 Genome accession   NZ_CP046523
Coordinates   1792045..1793994 (-) Length   649 a.a.
NCBI ID   WP_235097416.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOD     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1787045..1798994
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM48_RS09025 (GOM48_08960) - 1787415..1787762 (+) 348 WP_213988578.1 hypothetical protein -
  GOM48_RS09030 (GOM48_08965) - 1787919..1788953 (+) 1035 WP_235097411.1 S66 peptidase family protein -
  GOM48_RS09035 (GOM48_08970) - 1789059..1789322 (+) 264 WP_000166112.1 SemiSWEET family transporter -
  GOM48_RS09040 (GOM48_08975) - 1789394..1790077 (-) 684 WP_235097413.1 CPBP family intramembrane glutamic endopeptidase -
  GOM48_RS09045 (GOM48_08980) - 1790074..1790637 (-) 564 WP_235097415.1 DNA-3-methyladenine glycosylase I -
  GOM48_RS09050 (GOM48_08985) ruvA 1790647..1791240 (-) 594 WP_084925449.1 Holliday junction branch migration protein RuvA Machinery gene
  GOM48_RS09055 (GOM48_08990) - 1791399..1791896 (+) 498 WP_235098764.1 helix-turn-helix domain-containing protein -
  GOM48_RS09060 (GOM48_08995) hexB 1792045..1793994 (-) 1950 WP_235097416.1 DNA mismatch repair endonuclease MutL Machinery gene
  GOM48_RS09065 (GOM48_09000) - 1794203..1794643 (+) 441 WP_235097418.1 LytTR family DNA-binding domain-containing protein -
  GOM48_RS09070 (GOM48_09005) - 1794640..1795098 (+) 459 WP_235097420.1 DUF3021 domain-containing protein -
  GOM48_RS09075 (GOM48_09010) hexA 1795141..1797675 (-) 2535 WP_235097422.1 DNA mismatch repair protein MutS Machinery gene
  GOM48_RS09080 (GOM48_09015) argR 1797726..1798172 (-) 447 WP_061418468.1 arginine repressor -

Sequence

Protein


Download         Length: 649 a.a.        Molecular weight: 73332.75 Da        Isoelectric Point: 5.5277

>NTDB_id=352745 GOM48_RS09060 WP_235097416.1 1792045..1793994(-) (hexB) [Streptococcus oralis strain SOD]
MSHIIELPEVLANQIAAGEVIERPASVVKELVENAIDAGSSQIIIEIEEAGLKKIQITDNGHGIAHDEVELALRRHATSK
IKNQADLFRIRTLGFRGEALPSIASVSVLTLLTAVDGASHGTKLVARGGQVEEVIPATSPVGTKVCVEDLFFNTPARLKY
MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLASAKKMIAIENSDLDFEITGFVSLP
ELTRANRNYISLFINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKERELMALLSE
AISNSLKEQALIPDALENLAKSTVRNRQKVEQTILPLKENTLYYEKTEVTRPSQAEVADHQVELTEDGQDLTLFAKETLD
QLTKPAKLHFAERKPANYDQLDHPELDLASLDKAYDKLEREESSSFPELEFFGQMHGTYLFAQGRDGLYIIDQHAAQERV
KYEEYRESIGNVDQSQQQLLVPYIFEFPADDALRLRERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCD
MLLLTKEVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHFTKSDMEKMFRRIQENH
TSLRELGKY

Nucleotide


Download         Length: 1950 bp        

>NTDB_id=352745 GOM48_RS09060 WP_235097416.1 1792045..1793994(-) (hexB) [Streptococcus oralis strain SOD]
ATGTCTCATATTATTGAATTGCCAGAGGTGCTGGCAAACCAAATCGCGGCAGGAGAGGTCATTGAACGTCCTGCCAGTGT
AGTCAAAGAGTTGGTAGAAAATGCCATTGACGCGGGCTCTAGCCAGATTATCATTGAGATTGAGGAAGCTGGTCTCAAGA
AAATCCAAATCACAGATAATGGTCATGGAATTGCCCACGATGAGGTGGAGTTGGCCTTGCGTCGCCATGCGACCAGTAAG
ATAAAAAATCAAGCTGATCTCTTTCGGATTCGGACGCTTGGATTTCGAGGTGAAGCCCTGCCCTCTATCGCCTCTGTTAG
TGTGCTGACTCTGTTGACGGCGGTGGATGGTGCGAGTCATGGGACCAAGCTCGTTGCGCGTGGAGGTCAAGTTGAGGAAG
TCATCCCAGCGACTAGTCCTGTGGGGACCAAAGTTTGTGTGGAGGACCTCTTTTTCAACACGCCTGCCCGCCTCAAGTAT
ATGAAGAGCCAGCAAGCGGAGTTGTCTCATATCATTGATATTGTTAACCGTCTGGGATTGGCTCATCCTGAGATTTCTTT
TAGTTTGATCAGTGATGGCAAGGAAATGACACGGACAGCAGGGACTGGTCAACTACGCCAAGCCATCGCAGGGATTTACG
GTTTGGCGAGTGCTAAGAAGATGATTGCCATTGAGAACTCTGATTTAGATTTCGAAATTACAGGTTTTGTGTCTTTACCT
GAATTGACTCGAGCTAATCGCAACTATATCAGTCTCTTCATCAATGGTCGTTATATCAAGAACTTCCTGCTCAATCGTGC
CATTTTAGATGGTTATGGAAGCAAGCTCATGGTAGGTCGTTTTCCACTGGCAGTCATTCACATCCATATCGATCCTTATC
TGGCTGATGTCAATGTGCATCCAACCAAACAAGAAGTGCGGATTTCTAAGGAAAGAGAACTGATGGCGCTGCTTTCAGAA
GCTATTTCAAATAGTCTCAAGGAACAAGCCTTAATCCCTGATGCCTTGGAAAATCTTGCCAAATCGACCGTGCGCAATCG
TCAAAAGGTAGAGCAGACCATTCTTCCACTCAAAGAAAATACGCTTTACTATGAAAAAACAGAGGTAACAAGACCCAGTC
AAGCTGAGGTAGCTGATCATCAGGTTGAATTAACTGAGGATGGGCAGGATTTAACCCTGTTTGCCAAGGAAACCTTGGAC
CAGTTGACCAAGCCTGCAAAACTGCATTTTGCAGAGAGGAAACCAGCTAACTATGACCAACTAGACCATCCAGAGCTAGA
CCTTGCCAGTCTGGATAAGGCCTATGACAAGCTGGAGAGAGAAGAATCATCAAGCTTCCCAGAGTTGGAATTTTTTGGAC
AAATGCACGGGACTTATCTCTTTGCCCAAGGGCGAGATGGGCTCTACATCATAGACCAGCACGCGGCTCAGGAAAGGGTC
AAGTACGAGGAATACCGTGAAAGCATTGGGAATGTTGACCAGAGTCAGCAGCAACTCCTAGTACCTTACATCTTTGAGTT
TCCTGCGGATGATGCCCTTCGTCTTAGAGAAAGAATGCCTCTCTTAGAGGAAGTGGGCGTCTTTCTAGCAGAGTACGGAG
AAAATCAATTTATTCTACGTGAACATCCTATTTGGATGGCAGAGGAAGAAATCGAGTCTGGCATCTATGAAATGTGTGAC
ATGCTGCTCTTGACCAAGGAAGTTTCTATCAAGAAATACCGAGCGGAGCTGGCTATCATGATGTCCTGCAAGCGGTCTAT
CAAGGCCAATCACCGTATCGATGACCACTCAGCCAGACAGCTCCTTTATCAGCTCTCTCAATGCGACAACCCATATAACT
GTCCTCATGGACGTCCTGTTTTGGTGCATTTCACCAAGTCGGATATGGAAAAAATGTTCCGACGCATTCAGGAAAATCAT
ACTAGCCTCCGTGAGTTGGGGAAATATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-107)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(450-592)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

96.456

100

0.965

Multiple sequence alignment