Detailed information NTG0352730

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ES298_RS09785
• Genome accession: NZ_CP038253
• Coordinates: 1896741..1897751 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain TVO_1901929
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1891741..1902751

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES298_RS09760 (ES298_10300)	-	1892906..1893200 (-)	295	Protein_1933	hypothetical protein	-
ES298_RS09765 (ES298_10305)	-	1893362..1893814 (+)	453	WP_000079148.1	universal stress protein	-
ES298_RS09770 (ES298_10310)	-	1893849..1895237 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
ES298_RS09775 (ES298_10315)	-	1895303..1896265 (+)	963	WP_001124786.1	asparaginase	-
ES298_RS09780 (ES298_10320)	-	1896294..1896677 (-)	384	WP_001092022.1	hypothetical protein	-
ES298_RS09785 (ES298_10325)	ccpA	1896741..1897751 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
ES298_RS09790 (ES298_10330)	-	1898176..1898775 (-)	600	WP_000866703.1	response regulator transcription factor	-
ES298_RS09795 (ES298_10335)	-	1898776..1899873 (-)	1098	WP_000893503.1	sensor histidine kinase	-
ES298_RS09800 (ES298_10340)	-	1899873..1900610 (-)	738	WP_000832916.1	ABC transporter permease	-
ES298_RS09805 (ES298_10345)	-	1900612..1901496 (-)	885	WP_000219359.1	ABC transporter ATP-binding protein	-
ES298_RS09810 (ES298_10350)	-	1901483..1901677 (-)	195	WP_000715302.1	hypothetical protein	-
ES298_RS09815 (ES298_10355)	-	1901674..1901880 (-)	207	Protein_1944	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=352730 ES298_RS09785 WP_000990607.1 1896741..1897751(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901929]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=352730 ES298_RS09785 WP_000990607.1 1896741..1897751(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901929]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568