Detailed information NTG0352729

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ES298_RS09625
• Genome accession: NZ_CP038253
• Coordinates: 1868925..1869962 (-)
• Length: 345 a.a.
• NCBI ID: WP_001813016.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901929
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1863925..1874962

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES298_RS09600 (ES298_10115)	-	1864664..1865995 (-)	1332	WP_000390042.1	hemolysin family protein	-
ES298_RS09605 (ES298_10120)	endA	1866286..1867110 (-)	825	WP_001036791.1	DNA-entry nuclease EndA	Machinery gene
ES298_RS09610 (ES298_10125)	-	1867149..1867337 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
ES298_RS09615 (ES298_10130)	murA	1867330..1868613 (-)	1284	WP_000358032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ES298_RS09620 (ES298_10135)	-	1868637..1868867 (-)	231	WP_000250390.1	DUF1146 family protein	-
ES298_RS09625 (ES298_10140)	sepM	1868925..1869962 (-)	1038	WP_001813016.1	SepM family pheromone-processing serine protease	Regulator
ES298_RS09630 (ES298_10145)	coaD	1869946..1870434 (-)	489	WP_001280746.1	pantetheine-phosphate adenylyltransferase	-
ES298_RS09635 (ES298_10150)	rsmD	1870424..1870963 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ES298_RS09640 (ES298_10155)	asnA	1871028..1872020 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
ES298_RS09645 (ES298_10165)	-	1872132..1872815 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
ES298_RS09650 (ES298_10170)	-	1872871..1873611 (-)	741	WP_000152679.1	RNA methyltransferase	-
ES298_RS09655 (ES298_10175)	-	1873645..1873923 (+)	279	WP_001174614.1	acylphosphatase	-
ES298_RS09660 (ES298_10180)	yidC	1874001..1874927 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37609.64 Da
• Isoelectric Point: 4.9590

>NTDB_id=352729 ES298_RS09625 WP_001813016.1 1868925..1869962(-) (sepM) [Streptococcus pneumoniae strain TVO_1901929]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKEIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIDLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=352729 ES298_RS09625 WP_001813016.1 1868925..1869962(-) (sepM) [Streptococcus pneumoniae strain TVO_1901929]
ATGAAAAAAAAGATTAGATGGCCTTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGAAATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGACTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588