Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ES298_RS01885 Genome accession   NZ_CP038253
Coordinates   363329..364018 (+) Length   229 a.a.
NCBI ID   WP_000518010.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901929     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 358329..369018
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES298_RS01860 (ES298_01950) gpsB 358438..358767 (+) 330 WP_000146522.1 cell division regulator GpsB -
  ES298_RS01870 (ES298_01960) - 359253..360410 (+) 1158 WP_000711389.1 class I SAM-dependent RNA methyltransferase -
  ES298_RS01875 (ES298_01965) mapZ 360423..361817 (+) 1395 WP_000039268.1 mid-cell-anchored protein MapZ -
  ES298_RS01880 (ES298_01970) gndA 361893..363317 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  ES298_RS01885 (ES298_01975) covR 363329..364018 (+) 690 WP_000518010.1 response regulator transcription factor Regulator
  ES298_RS01890 (ES298_01980) cbpC 364116..365135 (+) 1020 WP_000771115.1 choline-binding protein CbpC -
  ES298_RS01895 (ES298_01985) mvk 365257..366135 (+) 879 WP_000163315.1 mevalonate kinase -
  ES298_RS01900 (ES298_01990) mvaD 366117..367070 (+) 954 WP_000373458.1 diphosphomevalonate decarboxylase -
  ES298_RS01905 (ES298_01995) - 367057..368064 (+) 1008 WP_000562430.1 phosphomevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26862.16 Da        Isoelectric Point: 6.9836

>NTDB_id=352681 ES298_RS01885 WP_000518010.1 363329..364018(+) (covR) [Streptococcus pneumoniae strain TVO_1901929]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTIQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=352681 ES298_RS01885 WP_000518010.1 363329..364018(+) (covR) [Streptococcus pneumoniae strain TVO_1901929]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATTCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment