Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   GE024_RS05980 Genome accession   NZ_CP046521
Coordinates   1177502..1179286 (-) Length   594 a.a.
NCBI ID   WP_093998577.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_100     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1172502..1184286
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE024_RS05965 (GE024_05970) pepV 1173178..1174587 (-) 1410 WP_093998579.1 dipeptidase PepV -
  GE024_RS05970 (GE024_05975) - 1174793..1175395 (-) 603 WP_003048214.1 nitroreductase family protein -
  GE024_RS05975 (GE024_05980) spxB 1175709..1177448 (+) 1740 WP_093998578.1 pyruvate oxidase -
  GE024_RS05980 (GE024_05985) uvrC 1177502..1179286 (-) 1785 WP_093998577.1 excinuclease ABC subunit UvrC Machinery gene
  GE024_RS05985 (GE024_05990) - 1179476..1179685 (-) 210 WP_081587266.1 hypothetical protein -
  GE024_RS05990 (GE024_05995) - 1179708..1181084 (-) 1377 WP_093998576.1 NAD-dependent succinate-semialdehyde dehydrogenase -
  GE024_RS05995 (GE024_06000) - 1181162..1181869 (-) 708 WP_093998575.1 YjjG family noncanonical pyrimidine nucleotidase -
  GE024_RS06000 (GE024_06005) - 1181885..1182451 (-) 567 WP_093998574.1 sugar O-acetyltransferase -
  GE024_RS06005 (GE024_06010) - 1182627..1183133 (-) 507 WP_093998573.1 YkgJ family cysteine cluster protein -
  GE024_RS06010 (GE024_06015) - 1183228..1184274 (-) 1047 WP_093998572.1 extracellular solute-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 67857.46 Da        Isoelectric Point: 9.4867

>NTDB_id=352596 GE024_RS05980 WP_093998577.1 1177502..1179286(-) (uvrC) [Streptococcus canis strain HL_100]
MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKNRVRSYFRGSHDTKTALLVSEIADFEFIVTESNTEALLLEIN
LIQENMPKYNIKLKDDKSYPFIKITNETFPRLLITRQIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPVNKVCF
YYHLGQCCAHTICHTDKAYWDGLVEEVKHFLNGKDDKIIDGLRAKMLAASEEMAFERAAEYRDLISGIATMRTKQRVMSK
DLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNEAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAI
VPTQIIKPKRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIENIGHLLGIDKPLRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKNEGLIAPNLIIIDGGQGQVNVAREVIANQLGLSIPIAGLQ
KNDKHQTHELLFGNPLEVVALPRNSEEFFLLQRIQDEVHRFAITFHRQVRSKNSFSSKLDKIPGLGPKRKQALLKHFKTM
TAIAAASPDEIQTLGIPKAVAQAIHQHVTDSQQS

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=352596 GE024_RS05980 WP_093998577.1 1177502..1179286(-) (uvrC) [Streptococcus canis strain HL_100]
ATGAACGAACTGATTAAACACAAGCTAGAACTCTTGCCAGATAGCCCTGGTTGCTACTTGCACAAGGATAAAGAGGGAAC
CATTATCTATGTAGGCAAGGCTAAGAATTTGAAGAACCGAGTGCGGTCTTATTTTCGTGGTAGCCATGATACCAAGACAG
CATTATTGGTGTCTGAGATTGCTGATTTTGAATTTATTGTCACCGAATCAAATACTGAGGCACTCTTACTTGAAATCAAC
TTGATTCAAGAAAACATGCCCAAGTATAATATCAAGCTCAAAGACGACAAGTCTTATCCCTTTATCAAAATCACCAATGA
GACCTTTCCTCGCCTGCTCATTACGAGACAAATTAAGAAAAATGACGGCCTGTATTTTGGGCCCTATCCAGATTCTTACA
CCGCTAACGAAGTGAAAAAATTGCTGGATCGCATTTTTCCCTTTAAGAAATGTAAAAACCCTGTCAATAAGGTCTGTTTT
TATTACCATTTAGGGCAGTGCTGTGCTCATACCATTTGCCATACGGATAAAGCTTATTGGGACGGTCTGGTAGAGGAAGT
CAAACACTTTTTGAATGGCAAGGATGATAAAATTATTGACGGGCTGCGTGCAAAAATGTTAGCAGCTTCTGAGGAAATGG
CATTTGAACGTGCGGCTGAGTATCGAGATTTGATTTCAGGTATTGCCACCATGCGCACCAAGCAGCGAGTGATGAGCAAG
GACTTGCAAGACAGGGATATTTTTGGTTACTTTGTTGACAAAGGTTGGATGTGCGTGCAGGTTTTCTTTGTCCGTCAAGG
AAAATTGATTCAGCGTGATGTCAACCTTTTTCCCTACTATAACGAGGCAGAAGAAGATTTTTTAACCTATATGGGGCAGT
TTTACCAAGATAAACAGCATTTCATTCCTAAAGAAGTCTTCATTCCAGAAGCTATTGATGAAGAATTAGTAGCCGCTATT
GTGCCAACCCAAATCATCAAACCCAAACGAGGTGAGAAAAAACAGCTGGTGGCTTTGGCTACTAAGAATGCCCGCGTCAG
CCTTCAGCAGAAATTTGATTTGTTGGAAAAAGATATTAAGAAAACTAGCGGTGCTATTGAAAATATAGGCCACTTGTTAG
GGATTGACAAGCCTTTGCGTATTGAAGCCTTTGATAATTCCAATATTCAAGGGACAAGCCCCGTAGCGGCTATGGTTGTT
TTTGTTGACGGGAAACCTAGTAAGAAAGATTACCGTAAATTTAAGATTAAAACAGTGGTGGGCCCAGATGATTATGCTAG
CATGAGAGAAGTGCTTTTTCGAAGGTATAGTCGCGTCAAAAATGAAGGGTTGATCGCCCCTAATTTGATTATTATTGACG
GCGGTCAGGGACAAGTCAATGTGGCAAGGGAAGTGATTGCAAACCAATTAGGTCTCAGTATTCCTATCGCAGGTTTACAA
AAAAATGATAAGCACCAAACCCATGAATTGCTCTTTGGCAATCCTCTTGAGGTGGTTGCCTTGCCTCGCAATTCAGAAGA
ATTTTTCCTCTTGCAACGGATTCAAGATGAGGTGCACCGTTTTGCCATTACCTTTCATCGTCAGGTACGTAGCAAGAATT
CTTTCTCATCGAAATTGGATAAGATTCCAGGACTCGGTCCAAAGCGCAAGCAGGCACTGCTTAAGCATTTTAAAACCATG
ACTGCCATTGCGGCAGCTAGTCCAGATGAAATTCAAACTTTAGGGATTCCTAAAGCGGTAGCACAAGCCATTCATCAGCA
CGTAACGGACAGTCAGCAAAGTTGA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(373-523)

UvrB/uvrC motif (UVR)

(196-228)

Helix-hairpin-helix domain (HHH_5)

(538-585)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

75.042

99.158

0.744
  uvrC Streptococcus pneumoniae R6

74.703

99.158

0.741
  uvrC Streptococcus pneumoniae D39

74.703

99.158

0.741

Multiple sequence alignment