Detailed information NTG0352495

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EOJ31_RS04600
• Genome accession: NZ_CP038242
• Coordinates: 953519..954562 (+)
• Length: 347 a.a.
• NCBI ID: WP_002466111.1
• Uniprot ID: A0A5F0TYQ0
• Organism: Staphylococcus warneri strain GD01
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 948519..959562

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EOJ31_RS04575	-	949575..950300 (+)	726	WP_019235971.1	type 1 glutamine amidotransferase	-
EOJ31_RS04580	-	950368..951354 (-)	987	WP_015364857.1	aromatic acid exporter family protein	-
EOJ31_RS04585	map	951521..952276 (+)	756	WP_002466104.1	type I methionyl aminopeptidase	-
EOJ31_RS04590	-	952420..952806 (+)	387	WP_002466133.1	DUF2543 family protein	-
EOJ31_RS04595	liaF	952821..953522 (+)	702	WP_015364858.1	cell wall-active antibiotics response protein LiaF	-
EOJ31_RS04600	vraS	953519..954562 (+)	1044	WP_002466111.1	sensor histidine kinase	Regulator
EOJ31_RS04605	vraR	954552..955181 (+)	630	WP_002466112.1	two-component system response regulator VraR	Regulator
EOJ31_RS04610	-	955240..956475 (-)	1236	WP_015364859.1	YihY/virulence factor BrkB family protein	-
EOJ31_RS04615	-	956705..956989 (-)	285	WP_002466132.1	YtxH domain-containing protein	-
EOJ31_RS04620	-	956997..957461 (-)	465	WP_002466141.1	low molecular weight protein-tyrosine-phosphatase	-
EOJ31_RS04625	-	957608..957811 (+)	204	WP_002466135.1	DUF1128 domain-containing protein	-
EOJ31_RS04630	-	957824..959065 (+)	1242	WP_015364860.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40087.57 Da
• Isoelectric Point: 6.2449

>NTDB_id=352495 EOJ31_RS04600 WP_002466111.1 953519..954562(+) (vraS) [Staphylococcus warneri strain GD01]
MNHYIRAIGSMLILIYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWIKT
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=352495 EOJ31_RS04600 WP_002466111.1 953519..954562(+) (vraS) [Staphylococcus warneri strain GD01]
ATGAATCACTATATAAGAGCTATTGGGTCAATGCTGATATTGATATATAGTATGTTAACGGCGTTCTTATTTATTGATAA
AGTTTTTGTCAACATCATTTACTTTCAAGGAATGTTTTATACACAAATTTTCGGTATTCCAGTGTTCTTATTTTTAAATA
TTATAGTTATATTATTATGTATTATAGTTGGATCAGTTCTAGCATATAAAATTAATCAACAGAATGATTGGATTAAAACT
CAAATTGAGCGATCAATTGAAGGGGAAACTGTTGGAATTAATGATCAAAATATTGAATTGTATAGCGAGACGTTAGAAAT
ATATCATACACTTGTCCCGTTAAATCAAGAGTTACATCGATTAAGAATGAAAACACAAAATTTAACTAACGAAAATTACA
ATATGAATGATGTTAAAGTTAAAAAGATTATTGAAGATGAGCGACAACGCTTAGCTAGAGAATTACATGATTCTGTAAGC
CAACAATTATTCGCTGCGAGTATGATGTTATCTGCAATAAAAGAAACACAGTTAGAACCACCATTAGATCAACAAATACC
CGTACTTGAAAAGATGGTCCAAGATTCACAACTAGAGATGAGAGCATTGTTACTTCATTTAAGACCATTAGGATTAAAAG
ATAAATCATTAGGTGAAGGTATTAAAGATTTAGTCATTGACCTTCAAAAGAAAGTACCAATGAAAGTAGTGCATGAAATT
CAAGAATTTAAAGTGCCAAAAGGAATTGAGGATCATTTATTCAGAATTACACAAGAAGCAATTTCAAATACATTGAGACA
TTCTAATGGCACAAGAGTAACGGTTGAATTATTTAATAAGCAAGATTATCTGCTTTTACGTATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAGAAACTTGAACAAAGTTATGGATTAAAGAATATGCGTGAACGTGCACTAGAAATTGGTGCTACC
TTCCATATCGTATCGTTACCAGACTCTGGTACACGTATTGAAGTTAAAGCACCATTAAACAAGGAGGATTCGTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A5F0TYQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.813	100	0.948