Detailed information NTG0352487

Bioinformatically predicted

Overview

• Name: ccrA
• Type: Machinery gene
• Locus tag: EOJ31_RS00200
• Genome accession: NZ_CP038242
• Coordinates: 42555..43904 (-)
• Length: 449 a.a.
• NCBI ID: WP_189723462.1
• Uniprot ID: -
• Organism: Staphylococcus warneri strain GD01
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	40906..49188	42555..43904	within	0

Gene organization within MGE regions

Location: 40906..49188

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EOJ31_RS00200	ccrA	42555..43904 (-)	1350	WP_189723462.1	cassette chromosome recombinase CcrA	Machinery gene
EOJ31_RS00205	cch1	44138..45931 (-)	1794	WP_189723464.1	cassette chromosome replicative helicase	-
EOJ31_RS00210	ssb	45931..46224 (-)	294	WP_001036501.1	cassette chromosome ssDNA-binding protein	-
EOJ31_RS00215	-	46457..47603 (+)	1147	Protein_40	IS3 family transposase	-
EOJ31_RS00220	-	47674..49188 (-)	1515	WP_189723466.1	hypothetical protein	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 52524.30 Da
• Isoelectric Point: 9.8649

>NTDB_id=352487 EOJ31_RS00200 WP_189723462.1 42555..43904(-) (ccrA) [Staphylococcus warneri strain GD01]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVKNGLQEKAKQGQLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNMYINRQPYQVRNIIINPNYCGRVINQYGQFDNMFPSIVSANV
YEQAQRLRLQKQTKQTPSDNQLKQKIKCPCCNATLTNMTVRKKNHILRYYVCPKNLNASRFVCDFKGINAQTLEDKVLKV
CQDFYQDQHIYAKIKNAIDKRLKRQRNTETHHTLTQEQLIEKLAQGIIDAETFRKQMQSLHQQPQRITSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide

• Length: 1350 bp

>NTDB_id=352487 EOJ31_RS00200 WP_189723462.1 42555..43904(-) (ccrA) [Staphylococcus warneri strain GD01]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAGGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACGCAATTAATTCAACAAGGGCAATGTGACATATTATGTTGTTATCGTCTTAATAGATTACATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAAAAATGGCCTTCAAGAAAAGGCAAAACAAGGTCAATTGATTACAACACATGCACCTTTTGGTTACGACTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGCCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACATGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTTATCAACCAATACGGTCAATTCGACAATATGTTCCCTTCTATTGTTTCAGCAAATGTA
TATGAACAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACACCTTCGGATAACCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCGTTAGAAAAAAGAATCATATATTACGTTACTACGTCTGTCCTA
AAAACTTGAATGCTTCACGCTTTGTCTGTGATTTCAAAGGCATCAATGCACAGACATTGGAAGATAAAGTATTGAAAGTG
TGCCAAGACTTTTATCAAGACCAACATATCTACGCAAAAATTAAAAATGCGATTGACAAACGCTTAAAAAGACAACGAAA
CACAGAAACACATCACACACTGACTCAAGAACAACTAATAGAAAAGTTAGCCCAAGGCATCATCGATGCAGAAACGTTCA
GAAAACAAATGCAATCATTACATCAACAACCGCAACGCATCACATCCATCAATGGGCATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (262-322)

• Resolvase, N terminal domain (Resolvase) (4-147)

• Recombinase (Recombinase) (169-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrA	Staphylococcus aureus N315	93.541	100	0.935
ccrA	Staphylococcus aureus COL	74.833	100	0.748