Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   E4J95_RS02495 Genome accession   NZ_CP038229
Coordinates   537414..537983 (+) Length   189 a.a.
NCBI ID   WP_045176736.1    Uniprot ID   -
Organism   Staphylococcus aureus strain MJ163     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 532414..542983
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E4J95_RS02470 (E4J95_02610) cysE 533627..534274 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  E4J95_RS02475 (E4J95_02615) cysS 534258..535658 (+) 1401 WP_000631963.1 cysteine--tRNA ligase -
  E4J95_RS02480 (E4J95_02620) - 535651..536055 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  E4J95_RS02485 (E4J95_02625) rlmB 536063..536809 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  E4J95_RS02490 (E4J95_02630) - 536809..537333 (+) 525 WP_000664738.1 NYN domain-containing protein -
  E4J95_RS02495 (E4J95_02635) sigH 537414..537983 (+) 570 WP_045176736.1 RNA polymerase sigma factor Regulator
  E4J95_RS02500 (E4J95_02640) rpmG 538098..538241 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  E4J95_RS02505 (E4J95_02645) secE 538297..538479 (+) 183 WP_169449250.1 preprotein translocase subunit SecE -
  E4J95_RS02510 (E4J95_02650) nusG 538492..539040 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  E4J95_RS02515 (E4J95_02655) rplK 539221..539643 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  E4J95_RS02520 (E4J95_02660) rplA 539851..540543 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  E4J95_RS02525 (E4J95_02670) rplJ 540815..541315 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  E4J95_RS02530 (E4J95_02675) rplL 541358..541726 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  E4J95_RS02535 (E4J95_02680) - 541901..542509 (+) 609 WP_023913388.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23113.96 Da        Isoelectric Point: 9.5790

>NTDB_id=352427 E4J95_RS02495 WP_045176736.1 537414..537983(+) (sigH) [Staphylococcus aureus strain MJ163]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQYKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=352427 E4J95_RS02495 WP_045176736.1 537414..537983(+) (sigH) [Staphylococcus aureus strain MJ163]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTATAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment