Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   GJV83_RS09675 Genome accession   NZ_CP046416
Coordinates   1986972..1987628 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain LZYWN_4     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1981972..1992628
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GJV83_RS09645 (GJV83_09655) dcyD 1982851..1983837 (+) 987 WP_001128205.1 D-cysteine desulfhydrase -
  GJV83_RS09650 (GJV83_09660) tcyL 1983852..1984520 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  GJV83_RS09655 (GJV83_09665) tcyN 1984517..1985269 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  GJV83_RS09660 (GJV83_09670) sdiA 1985499..1986221 (+) 723 WP_001154268.1 transcriptional regulator SdiA -
  GJV83_RS09665 (GJV83_09675) yecF 1986289..1986513 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  GJV83_RS09670 (GJV83_09680) yecU 1986500..1986676 (-) 177 WP_001307856.1 protein YecU -
  GJV83_RS24325 - 1986759..1986830 (-) 72 Protein_1915 transcriptional regulator -
  GJV83_RS09675 (GJV83_09685) letA 1986972..1987628 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  GJV83_RS09680 (GJV83_09690) uvrC 1987625..1989457 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  GJV83_RS09685 (GJV83_09695) pgsA 1989514..1990062 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  GJV83_RS09705 (GJV83_09715) - 1990758..1991498 (-) 741 WP_206970341.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=352264 GJV83_RS09675 WP_000611328.1 1986972..1987628(+) (letA) [Escherichia coli strain LZYWN_4]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=352264 GJV83_RS09675 WP_000611328.1 1986972..1987628(+) (letA) [Escherichia coli strain LZYWN_4]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482