Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   EXH44_RS02720 Genome accession   NZ_CP038145
Coordinates   567892..569184 (+) Length   430 a.a.
NCBI ID   WP_162856165.1    Uniprot ID   -
Organism   Actinobacillus indolicus strain AIFJ1607     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 562892..574184
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXH44_RS02695 (EXH44_02710) - 563011..565638 (-) 2628 WP_162856160.1 PBP1A family penicillin-binding protein -
  EXH44_RS02700 (EXH44_02715) comA 565795..566472 (+) 678 WP_162856161.1 competence protein ComA Machinery gene
  EXH44_RS02705 (EXH44_02720) comB 566448..566969 (+) 522 WP_162856162.1 hypothetical protein Machinery gene
  EXH44_RS02710 (EXH44_02725) comC 566966..567496 (+) 531 WP_162856163.1 ATPase Machinery gene
  EXH44_RS02715 (EXH44_02730) comD 567541..567882 (+) 342 WP_244238743.1 hypothetical protein Machinery gene
  EXH44_RS02720 (EXH44_02735) comE 567892..569184 (+) 1293 WP_162856165.1 type IV pilus secretin PilQ Machinery gene
  EXH44_RS02725 (EXH44_02740) nusB 569263..569676 (+) 414 WP_162856166.1 transcription antitermination factor NusB -
  EXH44_RS02730 (EXH44_02745) thiL 569685..570653 (+) 969 WP_162856167.1 thiamine-phosphate kinase -
  EXH44_RS02735 (EXH44_02750) - 570653..571126 (+) 474 WP_162857519.1 phosphatidylglycerophosphatase A -
  EXH44_RS02740 (EXH44_02755) - 571128..571748 (+) 621 WP_162856168.1 LysE family transporter -
  EXH44_RS02745 (EXH44_02760) - 571745..572683 (-) 939 WP_162856169.1 LacI family DNA-binding transcriptional regulator -
  EXH44_RS02750 (EXH44_02765) - 572683..573486 (-) 804 WP_162856170.1 pyruvate formate lyase-activating protein -
  EXH44_RS02755 (EXH44_02770) - 573665..573877 (+) 213 WP_162856171.1 YdcH family protein -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48163.25 Da        Isoelectric Point: 7.6907

>NTDB_id=351756 EXH44_RS02720 WP_162856165.1 567892..569184(+) (comE) [Actinobacillus indolicus strain AIFJ1607]
MRYLFLLFFATFPVLANQQISLSIKNSPTAEIIGYLAEETGKNITISDEIKDTKNFRVEKSHFDEILNSLVKTHQLHLKK
ENNIYYLSHKKEEENKNIANLTKPIVESAPSIPQPPKLITKTIKLHYSKASEVIESLTKGQGNLLSENGYIHFDDRSNSI
IVKDSAASVKNFTQLIQKLDKPTEQIAIEARIVTISSEHLQQLGVRWGLFSPNENHYKFAGNLEGNGLTTSNLNVNFPVT
PSASIALQIASINSRVLDLELTALERENNIEIIASPRLLTTDKKPASIKQGTEIPYAVYSKKEEMTDIEFREAVLGLEVT
PHISKQNQILLDLAISQNSPNNQMNNTMVTIDKQEINTQVLAKHGETIVLGGIFQHLISKGEDKVPILGSIPVIKTLFSQ
SQDKISKRELVIFVTPYIVKSEKIETGKLK

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=351756 EXH44_RS02720 WP_162856165.1 567892..569184(+) (comE) [Actinobacillus indolicus strain AIFJ1607]
ATGCGTTATTTATTCCTGCTATTCTTTGCTACCTTTCCTGTATTAGCAAACCAACAAATTTCGCTTTCTATAAAAAATTC
CCCTACAGCAGAAATTATTGGTTATTTGGCTGAAGAAACAGGAAAAAACATTACGATTTCAGATGAGATTAAAGATACGA
AAAACTTCAGAGTAGAAAAAAGCCATTTTGATGAAATCTTAAATAGTTTAGTTAAAACACACCAACTTCATTTAAAAAAG
GAAAATAATATTTATTACCTTAGCCATAAAAAAGAAGAAGAAAATAAAAATATCGCTAATTTAACGAAGCCAATAGTGGA
ATCAGCTCCGTCTATACCACAGCCCCCTAAATTAATTACCAAAACGATCAAATTACATTATTCCAAAGCATCAGAAGTGA
TCGAATCTTTAACCAAAGGACAGGGAAATTTACTCTCTGAGAATGGCTATATTCACTTTGATGATCGCAGTAATAGCATT
ATCGTCAAAGACAGTGCTGCTTCCGTTAAAAATTTTACTCAACTTATTCAGAAACTGGATAAACCAACGGAACAAATTGC
GATTGAAGCCCGAATTGTCACGATTAGTAGTGAACATTTACAACAACTTGGTGTACGTTGGGGCTTATTTTCTCCTAACG
AAAATCACTATAAATTTGCAGGAAATTTAGAAGGAAATGGATTAACCACCAGTAACTTAAATGTCAATTTTCCCGTAACG
CCGTCTGCTTCGATTGCCTTACAAATTGCATCAATCAATAGCCGTGTACTTGATTTAGAACTCACCGCATTGGAACGTGA
AAATAATATTGAAATTATTGCTAGCCCACGTTTACTGACAACGGACAAGAAGCCAGCAAGTATCAAACAAGGTACAGAGA
TTCCTTATGCCGTATATAGTAAGAAAGAAGAAATGACGGATATTGAATTTCGTGAAGCCGTTTTGGGGCTAGAAGTCACG
CCACATATCTCTAAACAAAATCAGATTTTGTTAGATCTCGCTATCAGCCAAAACTCCCCCAATAACCAAATGAATAATAC
GATGGTGACGATTGATAAACAGGAAATTAATACACAAGTCCTAGCCAAACACGGTGAGACTATTGTGTTAGGCGGTATTT
TTCAACACTTAATTTCCAAAGGCGAAGATAAAGTCCCTATTTTAGGCAGTATCCCTGTGATTAAAACCTTATTTAGCCAA
AGCCAAGATAAAATCTCTAAACGAGAATTAGTGATTTTTGTTACGCCTTACATTGTAAAATCTGAAAAAATAGAGACTGG
AAAACTGAAATAA

Domains

Predicted by InterProScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(120-185)

Bacterial type II and III secretion system protein (Secretin)

(263-420)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Glaesserella parasuis strain SC1401

87.442

100

0.874
  comE Haemophilus influenzae Rd KW20

52.184

100

0.528
  comE Haemophilus influenzae 86-028NP

51.27

100

0.516
  pilQ Vibrio campbellii strain DS40M4

37.237

99.302

0.37
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

37.47

97.442

0.365
  pilQ Vibrio cholerae strain A1552

37.47

97.442

0.365

Multiple sequence alignment