Detailed information NTG0351426

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: GL187_RS00290
• Genome accession: NZ_CP046379
• Coordinates: 44927..45820 (+)
• Length: 297 a.a.
• NCBI ID: WP_000343888.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 563
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 39927..50820

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL187_RS00260 (GL187_00260)	-	40240..41409 (+)	1170	WP_000366342.1	pyridoxal phosphate-dependent aminotransferase	-
GL187_RS00265 (GL187_00265)	recO	41406..42176 (+)	771	WP_000616164.1	DNA repair protein RecO	Machinery gene
GL187_RS00270 (GL187_00270)	plsX	42173..43165 (+)	993	WP_000717467.1	phosphate acyltransferase PlsX	-
GL187_RS00275 (GL187_00275)	-	43171..43404 (+)	234	WP_000136447.1	acyl carrier protein	-
GL187_RS00280 (GL187_00280)	-	43441..43740 (+)	300	Protein_47	transposase family protein	-
GL187_RS00285 (GL187_00285)	blpU	43943..44173 (+)	231	WP_001093487.1	bacteriocin-like peptide BlpU	-
GL187_RS11340	-	44176..44301 (+)	126	WP_000346297.1	PncF family bacteriocin immunity protein	-
GL187_RS10970	-	44712..44906 (+)	195	WP_000756776.1	hypothetical protein	-
GL187_RS00290 (GL187_00290)	comR	44927..45820 (+)	894	WP_000343888.1	helix-turn-helix domain-containing protein	Regulator
GL187_RS00295 (GL187_00295)	-	46363..46659 (+)	297	WP_000837726.1	uberolysin/carnocyclin family circular bacteriocin	-
GL187_RS00300 (GL187_00300)	-	46666..47802 (+)	1137	WP_000698828.1	hypothetical protein	-
GL187_RS00305 (GL187_00305)	-	47799..48281 (+)	483	WP_001232094.1	stage II sporulation protein M	-
GL187_RS00310 (GL187_00310)	-	48278..48874 (+)	597	WP_000687787.1	ATP-binding cassette domain-containing protein	-
GL187_RS00315 (GL187_00315)	-	48855..49346 (+)	492	WP_000671990.1	hypothetical protein	-

Sequence

Protein

• Length: 297 a.a.
• Molecular weight: 34517.01 Da
• Isoelectric Point: 4.6498

>NTDB_id=351426 GL187_RS00290 WP_000343888.1 44927..45820(+) (comR) [Streptococcus pneumoniae strain 563]
MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENGQALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFL
KLKDELIHSQTYADKGRIERKEAILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQTEDSLIYIQTFEKIIAKTRHVF
YRPHLFLLKAKYALFVDKNILEAESFYEKAISLAELLDDQVLVQRILAEKQIDFPTT

Nucleotide

• Length: 894 bp

>NTDB_id=351426 GL187_RS00290 WP_000343888.1 44927..45820(+) (comR) [Streptococcus pneumoniae strain 563]
ATGGATGAGTTGAAACGTGAAATTGGTTATAAAATCAAAACTATTAGGCGATCTTGTGGAAAAACTCAGATAGATATTTG
TGGTGATGAATCAGAGTTGACGATTCGTCAGCTAGCACGTATTGAAAATGGGCAAGCTTTAGCAACACTTCCTAAATTAT
TATTGATTGCGGATAAACTTGGAGTATCATTACAGAATATTGTGGATGTTAAGGTTATAGAGATTCCAAAAGGATTCCTA
AAACTCAAAGATGAGCTGATTCATTCTCAAACCTACGCTGATAAGGGAAGAATCGAACGAAAAGAAGCTATACTTGAGGA
AATATATGAAAACTATTATGAGAATTTGCCTGAGGAAGAGCAGTTAATTGTGGATGTGACACAAGCTCGTTTTGATATTT
ATGGTAGTTCAGATGTGACCTACGGTTTAGGGTTAGTGGAAGAATATTTCCAGCAGTTATTAAAAAAGAAATATTTTTCT
GTAAATGATTTGTTGATTATTGAATTGTATTTCTTTTGTTGTGCTATGGGATTAGAAGATAAAGAACATTTTGAGGAGTT
AGCTCAAAAAGTATTGCTATGTTCAGAATATGAAGATAAGGCTAGCCTAGTTCAAATGGAAAAAGTTCTTCTGAGCCTAT
TTATCCAAATTCAGACAGAAGATAGTCTGATATATATTCAAACATTTGAGAAAATTATTGCTAAAACAAGACATGTTTTT
TACCGACCTCATCTATTTTTGCTAAAGGCAAAATATGCTTTATTTGTAGACAAGAATATTTTAGAGGCAGAAAGTTTCTA
TGAAAAGGCGATTTCTCTAGCAGAATTGCTAGACGATCAGGTATTAGTTCAGAGAATTTTAGCAGAAAAACAGATAGATT
TCCCAACAACCTGA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (76-289)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	36.667	100	0.37