Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   E3C75_RS05475 Genome accession   NZ_CP038020
Coordinates   1038978..1040204 (+) Length   408 a.a.
NCBI ID   WP_084828584.1    Uniprot ID   A0A0E2Q2Z7
Organism   Streptococcus thermophilus strain ATCC 19258     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1033978..1045204
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3C75_RS05455 - 1034553..1035824 (-) 1272 WP_011680901.1 hydroxymethylglutaryl-CoA reductase, degradative -
  E3C75_RS05460 - 1035817..1036992 (-) 1176 WP_111679414.1 hydroxymethylglutaryl-CoA synthase -
  E3C75_RS05465 - 1037314..1038174 (+) 861 WP_084828582.1 thymidylate synthase -
  E3C75_RS05470 - 1038282..1038785 (+) 504 WP_011680903.1 dihydrofolate reductase -
  E3C75_RS11120 - 1038790..1038960 (+) 171 WP_002886174.1 hypothetical protein -
  E3C75_RS05475 clpX 1038978..1040204 (+) 1227 WP_084828584.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  E3C75_RS05480 yihA 1040214..1040813 (+) 600 WP_002950154.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  E3C75_RS05485 - 1040943..1042319 (+) 1377 WP_100273543.1 amino acid permease -
  E3C75_RS05490 mmuM 1042331..1043281 (+) 951 WP_100273104.1 homocysteine S-methyltransferase -
  E3C75_RS05495 - 1043394..1043648 (+) 255 WP_002950164.1 DUF1912 family protein -
  E3C75_RS05500 - 1043720..1044079 (+) 360 WP_084828587.1 helix-hairpin-helix domain-containing protein -
  E3C75_RS05505 plsY 1044197..1044838 (-) 642 WP_084828588.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45071.48 Da        Isoelectric Point: 4.4429

>NTDB_id=351410 E3C75_RS05475 WP_084828584.1 1038978..1040204(+) (clpX) [Streptococcus thermophilus strain ATCC 19258]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREETAEEVLADLAETPKPKELLDILNNYVVGQDRV
KRALAVAVYNHYKRINFTESREDHDVDLQKSNILMIGPTGSGKTYLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDESSYMKEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGK
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=351410 E3C75_RS05475 WP_084828584.1 1038978..1040204(+) (clpX) [Streptococcus thermophilus strain ATCC 19258]
ATGGCTGGAAATCGTAATGAAGAGATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTGAAGAAAATTATCGC
CGGTAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATTATTCGTGAGGAAACGGCTGAAGAAGTTT
TAGCTGACTTGGCTGAAACGCCAAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAAGATCGTGTC
AAACGTGCCTTGGCAGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGATCATGATGTGGA
CTTGCAAAAATCAAATATCCTCATGATTGGACCAACAGGGTCAGGGAAAACTTACTTAGCTCAGACTTTGGCTCGTAGTT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCAGGTTATGTGGGTGAGGATGTGGAAAATATCCTC
CTCAAACTAATCCAAGCGGCAGACTTTAATATTGAACGTGCGGAACGTGGGATTATCTACGTGGACGAGATTGATAAGAT
TGCCAAAAAAGGTGAGAATGTTTCAATCACTCGTGATGTTTCAGGTGAAGGGGTTCAACAAGCTCTCTTGAAGATTATTG
AGGGAACAGTGGCTAGCGTTCCACCTCAAGGTGGTCGTAAACACCCTAATCAAGAGATGATTCAAATTGATACTAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGGTT
TGGTCAAAATAATAAAGCAATTGATGACGAATCATCATACATGAAAGAAATTGTGGCTGAAGATATCCAAAAATTTGGAC
TTATCCCTGAATTTATCGGACGTTTGCCAGTTCTTGCGGCCCTTGAACAGTTAACGGTTGACGACTTGGTGCGTATTTTG
ACAGAGCCTAGGAATGCCTTGGTGAAGCAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCCCTTGAGGCTATTGCAAGTAAGGCAATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTTATGTTTGAAATCCCTAGTCAGGAAGATGTCACTAAGGTTCGTATCACCAAAGAAGCTGTTGATGGGAAA
GCTGCTCCAGTATTGGAAACAGCATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2Q2Z7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.998

100

0.892
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.757

99.755

0.566

Multiple sequence alignment