Detailed information NTG0351271

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: GL188_RS09320
• Genome accession: NZ_CP046359
• Coordinates: 1834305..1835342 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727276.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 573
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1829305..1840342

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL188_RS09295 (GL188_09450)	-	1830044..1831375 (-)	1332	WP_016398203.1	hemolysin family protein	-
GL188_RS09300 (GL188_09455)	endA	1831666..1832490 (-)	825	WP_001036786.1	DNA-entry nuclease EndA	Machinery gene
GL188_RS09305 (GL188_09460)	-	1832529..1832717 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
GL188_RS09310 (GL188_09465)	murA	1832710..1833993 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
GL188_RS09315 (GL188_09470)	-	1834017..1834247 (-)	231	WP_000250392.1	DUF1146 family protein	-
GL188_RS09320 (GL188_09475)	sepM	1834305..1835342 (-)	1038	WP_000727276.1	SepM family pheromone-processing serine protease	Regulator
GL188_RS09325 (GL188_09480)	coaD	1835326..1835814 (-)	489	WP_001280742.1	pantetheine-phosphate adenylyltransferase	-
GL188_RS09330 (GL188_09485)	rsmD	1835804..1836343 (-)	540	WP_000706962.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
GL188_RS09335 (GL188_09490)	asnA	1836408..1837400 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
GL188_RS09340 (GL188_09495)	-	1837512..1838195 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
GL188_RS09345 (GL188_09500)	-	1838251..1838991 (-)	741	WP_000152701.1	TrmH family RNA methyltransferase	-
GL188_RS09350 (GL188_09505)	-	1839025..1839303 (+)	279	WP_001174613.1	acylphosphatase	-
GL188_RS09355 (GL188_09510)	yidC	1839381..1840307 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37553.61 Da
• Isoelectric Point: 5.0724

>NTDB_id=351271 GL188_RS09320 WP_000727276.1 1834305..1835342(-) (sepM) [Streptococcus pneumoniae strain 573]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=351271 GL188_RS09320 WP_000727276.1 1834305..1835342(-) (sepM) [Streptococcus pneumoniae strain 573]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCTGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterProScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588