Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   GL188_RS00900 Genome accession   NZ_CP046359
Coordinates   168072..168512 (-) Length   146 a.a.
NCBI ID   WP_000861958.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 573     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 163072..173512
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL188_RS00875 (GL188_00925) - 163333..164619 (+) 1287 WP_000278870.1 response regulator transcription factor -
  GL188_RS00880 (GL188_00930) - 164671..165204 (+) 534 WP_000729029.1 ABC transporter permease -
  GL188_RS00885 (GL188_00935) nrdI 165282..165752 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  GL188_RS00890 (GL188_00940) - 166045..167307 (-) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  GL188_RS00895 (GL188_00945) - 167617..168075 (-) 459 WP_000745053.1 DUF3021 domain-containing protein -
  GL188_RS00900 (GL188_00950) brsR 168072..168512 (-) 441 WP_000861958.1 LytTR family DNA-binding domain-containing protein Regulator
  GL188_RS11210 - 168600..168725 (-) 126 WP_001822433.1 hypothetical protein -
  GL188_RS00905 (GL188_00960) hexB 168868..170817 (+) 1950 WP_000018179.1 DNA mismatch repair endonuclease MutL Machinery gene
  GL188_RS00910 (GL188_00965) ribE 171142..171609 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  GL188_RS00915 (GL188_00970) - 171610..172815 (-) 1206 WP_000456639.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  GL188_RS00920 (GL188_00975) ribE 172835..173470 (-) 636 WP_000493839.1 riboflavin synthase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17125.80 Da        Isoelectric Point: 5.9842

>NTDB_id=351192 GL188_RS00900 WP_000861958.1 168072..168512(-) (brsR) [Streptococcus pneumoniae strain 573]
MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQRGKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQILKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=351192 GL188_RS00900 WP_000861958.1 168072..168512(-) (brsR) [Streptococcus pneumoniae strain 573]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGGAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAACCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGATTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363