Detailed information NTG0351001

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: GL185_RS07230
• Genome accession: NZ_CP046357
• Coordinates: 1454484..1455377 (-)
• Length: 297 a.a.
• NCBI ID: WP_000343888.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 525
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1449484..1460377

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL185_RS07205 (GL185_07350)	-	1450958..1451449 (-)	492	WP_000671990.1	hypothetical protein	-
GL185_RS07210 (GL185_07355)	-	1451430..1452026 (-)	597	WP_000687787.1	ATP-binding cassette domain-containing protein	-
GL185_RS07215 (GL185_07360)	-	1452023..1452505 (-)	483	WP_001232094.1	stage II sporulation protein M	-
GL185_RS07220 (GL185_07365)	-	1452502..1453638 (-)	1137	WP_000698828.1	hypothetical protein	-
GL185_RS07225 (GL185_07370)	-	1453645..1453941 (-)	297	WP_000837726.1	uberolysin/carnocyclin family circular bacteriocin	-
GL185_RS07230 (GL185_07375)	comR	1454484..1455377 (-)	894	WP_000343888.1	XRE family transcriptional regulator	Regulator
GL185_RS11215	-	1455398..1455592 (-)	195	WP_000756776.1	hypothetical protein	-
GL185_RS11440	-	1456003..1456128 (-)	126	WP_000346297.1	PncF family bacteriocin immunity protein	-
GL185_RS07235 (GL185_07380)	blpU	1456131..1456361 (-)	231	WP_001093487.1	bacteriocin-like peptide BlpU	-
GL185_RS07240 (GL185_07385)	-	1456564..1456854 (-)	291	Protein_1458	IS5/IS1182 family transposase	-
GL185_RS07245 (GL185_07390)	-	1456900..1457133 (-)	234	WP_000136447.1	acyl carrier protein	-
GL185_RS07250 (GL185_07395)	plsX	1457139..1458131 (-)	993	WP_000717467.1	phosphate acyltransferase PlsX	-
GL185_RS07255 (GL185_07400)	recO	1458128..1458898 (-)	771	WP_000616164.1	DNA repair protein RecO	Machinery gene
GL185_RS07260 (GL185_07405)	-	1458895..1460064 (-)	1170	WP_000366342.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 297 a.a.
• Molecular weight: 34517.01 Da
• Isoelectric Point: 4.6498

>NTDB_id=351001 GL185_RS07230 WP_000343888.1 1454484..1455377(-) (comR) [Streptococcus pneumoniae strain 525]
MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENGQALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFL
KLKDELIHSQTYADKGRIERKEAILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQTEDSLIYIQTFEKIIAKTRHVF
YRPHLFLLKAKYALFVDKNILEAESFYEKAISLAELLDDQVLVQRILAEKQIDFPTT

Nucleotide

• Length: 894 bp

>NTDB_id=351001 GL185_RS07230 WP_000343888.1 1454484..1455377(-) (comR) [Streptococcus pneumoniae strain 525]
ATGGATGAGTTGAAACGTGAAATTGGTTATAAAATCAAAACTATTAGGCGATCTTGTGGAAAAACTCAGATAGATATTTG
TGGTGATGAATCAGAGTTGACGATTCGTCAGCTAGCACGTATTGAAAATGGGCAAGCTTTAGCAACACTTCCTAAATTAT
TATTGATTGCGGATAAACTTGGAGTATCATTACAGAATATTGTGGATGTTAAGGTTATAGAGATTCCAAAAGGATTCCTA
AAACTCAAAGATGAGCTGATTCATTCTCAAACCTACGCTGATAAGGGAAGAATCGAACGAAAAGAAGCTATACTTGAGGA
AATATATGAAAACTATTATGAGAATTTGCCTGAGGAAGAGCAGTTAATTGTGGATGTGACACAAGCTCGTTTTGATATTT
ATGGTAGTTCAGATGTGACCTACGGTTTAGGGTTAGTGGAAGAATATTTCCAGCAGTTATTAAAAAAGAAATATTTTTCT
GTAAATGATTTGTTGATTATTGAATTGTATTTCTTTTGTTGTGCTATGGGATTAGAAGATAAAGAACATTTTGAGGAGTT
AGCTCAAAAAGTATTGCTATGTTCAGAATATGAAGATAAGGCTAGCCTAGTTCAAATGGAAAAAGTTCTTCTGAGCCTAT
TTATCCAAATTCAGACAGAAGATAGTCTGATATATATTCAAACATTTGAGAAAATTATTGCTAAAACAAGACATGTTTTT
TACCGACCTCATCTATTTTTGCTAAAGGCAAAATATGCTTTATTTGTAGACAAGAATATTTTAGAGGCAGAAAGTTTCTA
TGAAAAGGCGATTTCTCTAGCAGAATTGCTAGACGATCAGGTATTAGTTCAGAGAATTTTAGCAGAAAAACAGATAGATT
TCCCAACAACCTGA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (76-289)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	36.667	100	0.37