Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   NMO_RS09450 Genome accession   NC_013016
Coordinates   1844632..1845492 (+) Length   286 a.a.
NCBI ID   WP_002220276.1    Uniprot ID   -
Organism   Neisseria meningitidis alpha14     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1839632..1850492
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMO_RS09435 (NMO_1706) dapD 1840142..1840963 (-) 822 WP_002224875.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase -
  NMO_RS12795 - 1840973..1841203 (-) 231 WP_002212338.1 hypothetical protein -
  NMO_RS09440 (NMO_1707) pgi 1841173..1842816 (-) 1644 WP_015815888.1 glucose-6-phosphate isomerase -
  NMO_RS09445 (NMO_1708) pilG 1843326..1844558 (+) 1233 WP_002216405.1 type 4 pilus assembly protein PilG Machinery gene
  NMO_RS09450 (NMO_1709) pilD 1844632..1845492 (+) 861 WP_002220276.1 prepilin peptidase Machinery gene
  NMO_RS09455 (NMO_1710) coaE 1845494..1846126 (+) 633 WP_002216402.1 dephospho-CoA kinase -
  NMO_RS09460 (NMO_1711) - 1846119..1846328 (+) 210 WP_002216401.1 DNA gyrase inhibitor YacG -
  NMO_RS09465 (NMO_1712) pilF 1846413..1848089 (-) 1677 WP_002221967.1 type IV-A pilus assembly ATPase PilB Machinery gene
  NMO_RS09475 (NMO_1713) - 1848581..1849027 (-) 447 WP_002220271.1 DUF441 domain-containing protein -
  NMO_RS09480 (NMO_1714) ispB 1849032..1850006 (-) 975 WP_002226981.1 octaprenyl diphosphate synthase -

Sequence

Protein


Download         Length: 286 a.a.        Molecular weight: 31359.40 Da        Isoelectric Point: 8.2213

>NTDB_id=34984 NMO_RS09450 WP_002220276.1 1844632..1845492(+) (pilD) [Neisseria meningitidis alpha14]
MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide


Download         Length: 861 bp        

>NTDB_id=34984 NMO_RS09450 WP_002220276.1 1844632..1845492(+) (pilD) [Neisseria meningitidis alpha14]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCGGTGTTCGGGCTGCTGGTCGGAAGTTTCTTAAA
TGTCGTCATTTACCGCGTGCCGGTCATGATGGAGCGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGCCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCCTCCTGCCAAACCAAAATCAGCATACGCTATCC
CTTAATCGAACTGCTGACCGGCGTATTGTTCGGGCTGGTTGCCTGGCAATACGGCTGGTCTTGGATTACATTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAATCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(17-124)

Type IV leader peptidase family (Peptidase_A24)

(134-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Neisseria gonorrhoeae MS11

96.14

99.65

0.958
  pilD Vibrio cholerae strain A1552

44.444

100

0.448
  pilD Vibrio campbellii strain DS40M4

44.928

96.503

0.434
  pilD Acinetobacter baumannii D1279779

46.97

92.308

0.434
  pilD Acinetobacter nosocomialis M2

46.97

92.308

0.434

Multiple sequence alignment