Detailed information    

insolico Bioinformatically predicted

Overview

Name   comS   Type   Regulator
Locus tag   EZ612_RS08870 Genome accession   NZ_CP036531
Coordinates   48107..48202 (+) Length   31 a.a.
NCBI ID   WP_198462994.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain STAB10048     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 43107..53202
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EZ612_RS00250 (EZ612_00250) purK 43177..44250 (+) 1074 WP_023611330.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  EZ612_RS00255 (EZ612_00255) - 44252..45670 (+) 1419 WP_023612101.1 hypothetical protein -
  EZ612_RS00260 (EZ612_00260) purB 45690..46982 (+) 1293 WP_023612104.1 adenylosuccinate lyase -
  EZ612_RS00265 (EZ612_00265) comR 47112..48023 (+) 912 WP_002986681.1 transcriptional regulator Rgg4/ComR Regulator
  EZ612_RS08870 comS 48107..48202 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  EZ612_RS00270 (EZ612_00270) ruvB 48249..49247 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB -
  EZ612_RS00275 (EZ612_00275) - 49385..49822 (+) 438 WP_020904819.1 low molecular weight protein-tyrosine-phosphatase -
  EZ612_RS00280 (EZ612_00280) - 49846..50247 (+) 402 WP_002986671.1 MORN repeat-containing protein -
  EZ612_RS00285 (EZ612_00285) - 50244..52019 (+) 1776 WP_014407199.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 31 a.a.        Molecular weight: 3857.66 Da        Isoelectric Point: 10.0436

>NTDB_id=349488 EZ612_RS08870 WP_198462994.1 48107..48202(+) (comS) [Streptococcus pyogenes strain STAB10048]
MLKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 96 bp        

>NTDB_id=349488 EZ612_RS08870 WP_198462994.1 48107..48202(+) (comS) [Streptococcus pyogenes strain STAB10048]
ATGTTAAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGCTGTTGA
CTGGTGGCGATTATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

100

100

1
  comS Streptococcus pyogenes MGAS315

45.161

100

0.452

Multiple sequence alignment