Detailed information    

insolico Bioinformatically predicted

Overview

Name   hapR   Type   Regulator
Locus tag   EZZ25_RS01500 Genome accession   NZ_CP036499
Coordinates   333040..333651 (+) Length   203 a.a.
NCBI ID   WP_000340100.1    Uniprot ID   Q4F6W7
Organism   Vibrio cholerae strain 20000     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 328040..338651
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EZZ25_RS01480 (EZZ25_01480) - 328376..329293 (-) 918 WP_000271070.1 ATP-binding cassette domain-containing protein -
  EZZ25_RS01485 (EZZ25_01485) - 329674..331320 (-) 1647 WP_000484915.1 SulP family inorganic anion transporter -
  EZZ25_RS01490 (EZZ25_01490) can 331468..332136 (+) 669 WP_001114117.1 carbonate dehydratase -
  EZZ25_RS01495 (EZZ25_01495) hpt 332211..332744 (-) 534 WP_000683351.1 hypoxanthine phosphoribosyltransferase -
  EZZ25_RS01500 (EZZ25_01500) hapR 333040..333651 (+) 612 WP_000340100.1 quorum-sensing master transcriptional regulator HapR Regulator
  EZZ25_RS01505 (EZZ25_01505) rsmI 333861..334727 (-) 867 WP_000131547.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  EZZ25_RS01510 (EZZ25_01510) - 334797..336602 (+) 1806 WP_001015477.1 penicillin-binding protein activator -
  EZZ25_RS01515 (EZZ25_01515) - 336589..336957 (+) 369 WP_001893625.1 YraN family protein -
  EZZ25_RS01520 (EZZ25_01520) - 336961..337551 (+) 591 WP_000887295.1 phosphoheptose isomerase -
  EZZ25_RS01525 (EZZ25_01525) - 337554..338123 (+) 570 WP_000836325.1 BON domain-containing protein -
  EZZ25_RS01530 (EZZ25_01530) tnpA 338207..338644 (-) 438 WP_131476896.1 IS200/IS605-like element IS1004 family transposase -

Sequence

Protein


Download         Length: 203 a.a.        Molecular weight: 23720.44 Da        Isoelectric Point: 6.6356

>NTDB_id=349207 EZZ25_RS01500 WP_000340100.1 333040..333651(+) (hapR) [Vibrio cholerae strain 20000]
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLVDSYLNMLCIYKN

Nucleotide


Download         Length: 612 bp        

>NTDB_id=349207 EZZ25_RS01500 WP_000340100.1 333040..333651(+) (hapR) [Vibrio cholerae strain 20000]
ATGGACGCATCAATCGAAAAACGCCCTCGAACTCGGCTATCGCCTCAAAAACGCAAACTACAACTGATGGAAATCGCGTT
GGAAGTGTTTGCTAAACGCGGCATTGGTCGTGGTGGTCACGCAGATATTGCCGAGATTGCGCAAGTCTCCGTTGCAACAG
TGTTCAACTACTTCCCAACTCGTGAAGACTTGGTTGACGATGTGCTGAATTTTGTGGTTCGTCAGTACTCCAACTTTTTG
ACCGATCACATCGATCTTGATTTGGATGTGAAAACCAACCTACAAACTCTGTGCAAAGAGATGGTGAAATTGGCGATGAC
CGATTGTCACTGGCTCAAAGTCTGGTTTGAGTGGAGTGCTTCAACCCGTGACGAAGTTTGGCCACTGTTTGTTTCCACCA
ACCGAACGAACCAACTGCTGATCAGAAACATGTTTATGAAAGCGATGGAACGTGGCGAATTGTGTGAGAAACACGATGTC
GATAACATGGCCAGCCTGTTCCACGGCATCTTCTACTCCATCTTCTTACAAGTGAACCGTTTAGGTGAACAAGAAGCAGT
GTATAAGTTGGTCGATAGCTACCTCAATATGCTGTGTATCTACAAGAACTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, tetR family (TetR_N)

(23-67)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4F6W7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hapR Vibrio cholerae C6706

99.507

100

0.995
  hapR Vibrio cholerae strain A1552

99.507

100

0.995
  opaR Vibrio parahaemolyticus RIMD 2210633

72.727

97.537

0.709

Multiple sequence alignment