Detailed information NTG0346868

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: EXW25_RS05855
• Genome accession: NZ_CP036111
• Coordinates: 1141442..1144042 (+)
• Length: 866 a.a.
• NCBI ID: WP_000365394.1
• Uniprot ID: A0AB36T830
• Organism: Bacillus toyonensis strain JAS411
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1136442..1149042

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EXW25_RS05815 (EXW25_05900)	-	1136686..1137027 (+)	342	WP_098054384.1	hypothetical protein	-
EXW25_RS05820 (EXW25_05905)	prsA	1137205..1138062 (-)	858	WP_001214219.1	peptidylprolyl isomerase PrsA	-
EXW25_RS05825 (EXW25_05910)	-	1138192..1138323 (-)	132	WP_001120851.1	DUF3941 domain-containing protein	-
EXW25_RS05830 (EXW25_05915)	-	1138424..1139281 (+)	858	WP_098099738.1	YitT family protein	-
EXW25_RS05835 (EXW25_05920)	-	1139307..1139504 (-)	198	WP_000527396.1	DUF3813 domain-containing protein	-
EXW25_RS05840 (EXW25_05925)	-	1139505..1139645 (-)	141	WP_000516816.1	hypothetical protein	-
EXW25_RS05845 (EXW25_05930)	-	1139750..1140559 (-)	810	WP_000043171.1	Cof-type HAD-IIB family hydrolase	-
EXW25_RS05850 (EXW25_05935)	-	1141052..1141231 (+)	180	WP_016082481.1	YjzC family protein	-
EXW25_RS05855 (EXW25_05940)	clpC	1141442..1144042 (+)	2601	WP_000365394.1	ATP-dependent chaperone ClpB	Regulator
EXW25_RS05860 (EXW25_05945)	-	1144079..1144261 (-)	183	WP_001211112.1	YjzD family protein	-
EXW25_RS05865 (EXW25_05950)	-	1144418..1145152 (+)	735	WP_000028709.1	hypothetical protein	-
EXW25_RS05870 (EXW25_05955)	-	1145182..1146054 (+)	873	WP_000486175.1	NAD(P)-dependent oxidoreductase	-
EXW25_RS05875 (EXW25_05960)	comZ	1146119..1146295 (+)	177	WP_001003338.1	ComZ family protein	Regulator
EXW25_RS05880 (EXW25_05965)	fabH	1146540..1147472 (+)	933	WP_001100553.1	beta-ketoacyl-ACP synthase III	-
EXW25_RS05885 (EXW25_05970)	fabF	1147503..1148741 (+)	1239	WP_000412641.1	beta-ketoacyl-ACP synthase II	-

Sequence

Protein

• Length: 866 a.a.
• Molecular weight: 97569.54 Da
• Isoelectric Point: 5.1950

>NTDB_id=346868 EXW25_RS05855 WP_000365394.1 1141442..1144042(+) (clpC) [Bacillus toyonensis strain JAS411]
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLLALLEEQDGLAVRIFQKMNVDIEALKQDVENVIKKKPSVTGSGAE
AGKLYVTSNLQQLLVRAGKEAEKLQDDYISVEHVLLAFSEEKGDINHLFTRLHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVRAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASSMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNKAAELRHGKIPAIEKELKEAEEMSAHNKQENRLLREEVSEEEIADIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLEADGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VELTDSAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK

Nucleotide

• Length: 2601 bp

>NTDB_id=346868 EXW25_RS05855 WP_000365394.1 1141442..1144042(+) (clpC) [Bacillus toyonensis strain JAS411]
ATGGACTTAAATCAAATGACAACGAAAACACAAGAGGCGATTATGAGTGCCCAATCTTTAGCGGTATCTCATCATCACCA
AGAGGTGGATACTGTTCATCTATTACTTGCATTATTAGAGGAGCAAGATGGATTAGCAGTACGTATATTTCAAAAAATGA
ATGTTGATATAGAAGCATTGAAGCAAGATGTAGAAAATGTAATTAAAAAGAAACCTTCTGTAACGGGAAGCGGAGCAGAA
GCTGGGAAATTGTATGTAACAAGCAATCTGCAGCAACTGCTTGTAAGAGCAGGGAAAGAAGCAGAAAAACTGCAGGATGA
TTACATTTCAGTAGAACATGTATTGCTTGCTTTTTCTGAAGAAAAAGGCGATATCAATCATTTATTTACAAGATTGCATA
TTACGAAAGATAACTTATTACAGTCTTTAATGACAGTTCGGGGGAATCAAAGAGTGACTAGTCAAAATCCAGAAGCAACT
TATGAAGCATTAGAAAAATATGGCCGTGATTTAGTGGCGGAAGTGAGAGCAGGGAAAATTGATCCTGTTATCGGACGAGA
TAGTGAAATTCGCCGCGTTATTCGCATTCTTTCACGTAAAACGAAAAACAACCCTGTTTTAATTGGTGAGCCAGGTGTTG
GTAAAACAGCAATTGTTGAAGGATTAGCACAGCGTATCGTGAAAAAAGATGTACCAGAAGGGTTAAAAGATAGAACAATC
TTTGCATTAGATATGAGTGCACTTGTAGCCGGAGCAAAATTCCGTGGTGAATTTGAAGAGCGCCTGCAAGCTGTATTAAA
TGAAATTAAAAAGAGTGAAGGCCGTATTTTATTATTCATTGATGAACTTCATACAATCGTCGGCGCTGGTAAAACAGAAG
GTGCGATGGACGCAGGAAATATGTTAAAACCGATGCTTGCTCGTGGTGAACTGCATTGTATCGGGGCAACGACATTAGAT
GAATATCGTAAATATATTGAGAAAGACCCAGCGTTAGAAAGACGTTTCCAACAAGTATTAGCAGAGGAACCGACTGTTGA
AGATACAATCTCCATTTTACGTGGTTTAAAAGAGCGTTTTGAAATTTATCACGGTGTAAATATTCATGACCGCGCGATTG
TAGCAGCATCTGTTTTATCAGATCGATATATTTCAGATCGCTTCTTACCGGATAAAGCAATTGACCTTGTTGACGAAGCA
TGCGCAACAATTCGTACAGAAATTGATTCTATGCCAACAGAATTAGATGAAGTAACGCGCCGTATTATGCAGCTGGAAAT
TGAAGAAGCCGCTCTTGGAAAAGAGAAGGACTTTGGTAGCCAAGAACGTCTAAAAACATTGCAACGTGAATTATCGGATT
TAAAAGAAGTTGCAAGTAGCATGAGAGCGAAATGGGAGAAAGAAAAAGAAGATATTCACAAAGTTCGTGACTTACGTGAA
CATTTAGAGCGTCTGCGCCGTGAATTAGAAGAAGCAGAAGGTAATTACGATTTAAATAAAGCAGCTGAACTTCGTCACGG
AAAAATTCCTGCAATTGAAAAAGAATTAAAAGAAGCGGAAGAAATGAGCGCACATAATAAACAAGAAAATCGTTTATTAC
GCGAGGAAGTCAGTGAAGAAGAAATTGCTGATATCGTTTCACGCTGGACTGGTATTCCTGTCGCAAAACTCGTTGAGGGT
GAACGTGAGAAATTACTACGCTTAGAGCAAATTTTATCAGAGCGTGTCATCGGACAAGAGGAAGCGGTAAGTTTAGTATC
AGACGCAGTTCTTCGTGCACGCGCTGGTATTAAAGACCCGAACCGTCCAATTGGTTCCTTCATTTTCTTAGGACCGACAG
GTGTTGGTAAAACAGAACTTGCAAAAACGTTAGCGCAGTCTTTATTCGATAGTGAAGAGCAAATGATTCGTATCGACATG
TCTGAGTATATGGAGAAACACGCTGTGTCACGCTTAATTGGTGCGCCTCCTGGATATGTTGGATATGAAGAGGGCGGTCA
ATTAACAGAGGCGGTAAGACGTAAACCATATTCCGTTATTTTGTTAGACGAAATCGAAAAAGCACATCCAGAAGTATTCA
ACATTTTATTACAAATGTTAGATGATGGACGCATTACAGATTCGCAAGGACGTACAGTAGACTTTAAAAACACGGTTATT
ATTATGACTTCAAATATTGGATCTGCTCATTTGTTAGATGGATTAGAAGCAGATGGCTCCATTAAAGAGGAATCAAGAGA
ACTTGTAATGGGGCAATTAAGAGGACATTTCCGACCAGAGTTCTTAAACCGTGTCGATGAAATTATTTTATTCAAACCGC
TTACAACGAATGAAATTAAAGGTATTGTTGATAAAATTGTAAAAGAATTACAAGGTCGTTTAGCTGACCGTCATATTACA
GTGGAATTAACGGATTCTGCAAAAGAATTTGTTGTAGAAGCTGGCTTTGATCCGATGTACGGAGCTCGTCCATTAAAACG
ATACGTACAGCGTCAAGTGGAAACGAAATTAGCGAGAGAATTAATTGCAGGCACAATTACGGATAATAGTCACGTAGTTG
TTGATGTAGAAAATAACGAATTAGTTGTTCATGTGAAATGA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (602-768)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (774-854)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (97-148)

• ATPase family associated with various cellular activities (AAA) (AAA) (206-339)

• AAA lid domain (AAA_lid_9) (345-447)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.657	100	0.482
clpC	Lactococcus lactis subsp. cremoris KW2	46.704	82.333	0.385