Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   SAVC_RS05245 Genome accession   NC_016912
Coordinates   1061360..1063141 (+) Length   593 a.a.
NCBI ID   WP_000390535.1    Uniprot ID   -
Organism   Staphylococcus aureus subsp. aureus VC40     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1056360..1068141
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAVC_RS05225 (SAVC_04880) polX 1056479..1058191 (+) 1713 WP_000161942.1 DNA polymerase/3'-5' exonuclease PolX -
  SAVC_RS05230 (SAVC_04885) mutS/mutS2 1058201..1060549 (+) 2349 WP_001249285.1 endonuclease MutS2 Machinery gene
  SAVC_RS05235 (SAVC_04890) trxA 1060722..1061036 (+) 315 WP_001018928.1 thioredoxin -
  SAVC_RS05240 - 1061099..1061194 (-) 96 WP_001788625.1 hypothetical protein -
  SAVC_RS05245 (SAVC_04895) uvrC 1061360..1063141 (+) 1782 WP_000390535.1 excinuclease ABC subunit UvrC Machinery gene
  SAVC_RS05250 (SAVC_04900) - 1063465..1064079 (+) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  SAVC_RS05255 (SAVC_04905) sdhA 1064131..1065897 (+) 1767 WP_000818278.1 succinate dehydrogenase flavoprotein subunit -
  SAVC_RS05260 (SAVC_04910) sdhB 1065897..1066712 (+) 816 WP_000139712.1 succinate dehydrogenase iron-sulfur subunit -
  SAVC_RS05265 (SAVC_04915) racE 1066948..1067748 (+) 801 WP_001039659.1 glutamate racemase -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68661.32 Da        Isoelectric Point: 9.7838

>NTDB_id=34669 SAVC_RS05245 WP_000390535.1 1061360..1063141(+) (uvrC) [Staphylococcus aureus subsp. aureus VC40]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMI
QSVVDTKIVQSARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSA
MVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGNKRKTLLLRSF
GSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=34669 SAVC_RS05245 WP_000390535.1 1061360..1063141(+) (uvrC) [Staphylococcus aureus subsp. aureus VC40]
TTGGAAGACTATAAGCAACGAATTAAAAATAAATTAAATGTCGTACCTATGGAACCAGGATGCTATTTAATGAAAGATCG
TAATGATCAAGTGATATATGTTGGCAAAGCTAAAAAGCTAAGAAATCGATTGCGATCATATTTTACGGGTGCTCATGATG
CTAAAACAACGAGACTGGTTGGTGAAATACGTCGCTTTGAGTTTATTGTCACGTCAAGTGAAACAGAATCACTTTTACTG
GAATTGAATCTGATTAAACAATATCAACCAAGATATAATATATTATTAAAGGATGATAAAAGTTATCCATTTATTAAAAT
TACGAAGGAGAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTGACAAACAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGATGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAGCGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGCTTAAACCAACATATTTTACCTAAGGAAGTTCATGTACCACGTAATTTGGATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAATCCGCGCGAGGTCCCAAAAAAGATATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCCAGAACGATTAAAGCTATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATTCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTGTCGACGGTAAACCAGATAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGACGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCTGATTTAATAA
TAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAGAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGCCAGGCATTTTATTTGTTGCACCGTATCCAAGATGAGGTTCACAGATTCGCAATCACATTTCATAGACAAACACGTC
AAAAGACAGGCTTGAAATCAATACTTGATGATATAGATGGTATCGGTAACAAACGTAAAACATTATTATTGCGTTCATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATATAGGTATTCCTGAAAACGTCGCAAAGAACCT
ACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(19-93)

UvrB/uvrC motif (UVR)

(200-233)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae R6

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae D39

57.265

98.651

0.565

Multiple sequence alignment