Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   EXW45_RS26720 Genome accession   NZ_CP036073
Coordinates   5175110..5175691 (+) Length   193 a.a.
NCBI ID   WP_001049163.1    Uniprot ID   A0A366GQ86
Organism   Bacillus wiedmannii strain JAS08/1     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 5170110..5180691
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXW45_RS26680 (EXW45_27165) - 5170547..5170900 (-) 354 WP_149293738.1 YxeA family protein -
  EXW45_RS26685 (EXW45_27170) - 5171106..5171312 (+) 207 WP_000216166.1 DUF1657 domain-containing protein -
  EXW45_RS26690 (EXW45_27175) - 5171406..5171891 (+) 486 WP_046955592.1 YhcN/YlaJ family sporulation lipoprotein -
  EXW45_RS26695 (EXW45_27180) spoVAC 5171921..5172397 (+) 477 WP_000095399.1 stage V sporulation protein AC -
  EXW45_RS26700 (EXW45_27185) spoVAD 5172398..5173414 (+) 1017 WP_149293737.1 stage V sporulation protein AD -
  EXW45_RS26705 (EXW45_27190) spoVAE 5173411..5173761 (+) 351 WP_000575918.1 stage V sporulation protein AE -
  EXW45_RS26710 (EXW45_27195) - 5173773..5173979 (+) 207 WP_000215899.1 DUF1657 domain-containing protein -
  EXW45_RS26715 (EXW45_27200) - 5174000..5174869 (+) 870 WP_046955590.1 DUF421 domain-containing protein -
  EXW45_RS26720 (EXW45_27205) clpP 5175110..5175691 (+) 582 WP_001049163.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  EXW45_RS26725 (EXW45_27215) - 5175975..5176223 (-) 249 WP_000250305.1 HPr family phosphocarrier protein -
  EXW45_RS26730 (EXW45_27220) whiA 5176247..5177197 (-) 951 WP_000006567.1 DNA-binding protein WhiA -
  EXW45_RS26735 (EXW45_27225) - 5177287..5178240 (-) 954 WP_060488060.1 YvcK family protein -
  EXW45_RS26740 (EXW45_27230) rapZ 5178244..5179125 (-) 882 WP_000138461.1 RNase adapter RapZ -
  EXW45_RS26745 (EXW45_27235) - 5179146..5179604 (-) 459 WP_001190080.1 8-oxo-dGTP diphosphatase -
  EXW45_RS26750 (EXW45_27240) - 5179833..5180639 (-) 807 WP_000455195.1 DUF368 domain-containing protein -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21447.68 Da        Isoelectric Point: 5.0423

>NTDB_id=346500 EXW45_RS26720 WP_001049163.1 5175110..5175691(+) (clpP) [Bacillus wiedmannii strain JAS08/1]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLESQDPEKDIHIYINSPGGSITAGMAIYDT
MQFIKPQVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILFLREKLNQILADRTGQ
PLEVLQRDTDRDNFMTAERALEYGLIDKIFTNR

Nucleotide


Download         Length: 582 bp        

>NTDB_id=346500 EXW45_RS26720 WP_001049163.1 5175110..5175691(+) (clpP) [Bacillus wiedmannii strain JAS08/1]
ATGAATTTAATTCCTACAGTAATTGAACAAACAAATCGTGGAGAACGCGCTTACGATATTTACTCTCGACTATTAAAAGA
CCGCATCATTATGCTTGGTAGTGCAATTGATGACAACGTAGCTAACTCAATCGTTTCCCAGCTTTTATTCTTGGAATCTC
AAGATCCAGAAAAAGATATTCACATCTACATCAATAGCCCTGGTGGTTCTATCACAGCAGGTATGGCAATTTACGATACA
ATGCAATTTATTAAACCACAAGTATCAACAATCTGTATCGGTATGGCTGCATCTATGGGTGCATTCTTACTTGCAGCAGG
TGAAAAAGGAAAACGTTATGCACTTCCAAACAGTGAAGTAATGATTCACCAACCACTTGGCGGAGCACAAGGTCAAGCGA
CTGAAATCGAAATCGCTGCAAAACGTATCCTATTCTTACGTGAAAAACTAAACCAAATTCTTGCTGACCGCACAGGTCAA
CCACTTGAAGTACTACAACGCGACACAGACCGCGACAACTTCATGACAGCTGAAAGAGCTCTAGAATACGGCTTAATCGA
TAAGATCTTTACAAATCGTTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A366GQ86

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

90.104

99.482

0.896
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

67.021

97.409

0.653
  clpP Streptococcus thermophilus LMG 18311

60.417

99.482

0.601
  clpP Streptococcus thermophilus LMD-9

60.417

99.482

0.601
  clpP Lactococcus lactis subsp. cremoris KW2

58.854

99.482

0.585
  clpP Streptococcus pneumoniae D39

57.292

99.482

0.57
  clpP Streptococcus pneumoniae Rx1

57.292

99.482

0.57
  clpP Streptococcus pneumoniae R6

57.292

99.482

0.57
  clpP Streptococcus pneumoniae TIGR4

57.292

99.482

0.57
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

56.771

99.482

0.565
  clpP Streptococcus pyogenes JRS4

55.729

99.482

0.554
  clpP Streptococcus pyogenes MGAS315

55.729

99.482

0.554
  clpP Streptococcus mutans UA159

55.44

100

0.554

Multiple sequence alignment