Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   GHT02_RS23615 Genome accession   NZ_CP045712
Coordinates   4898340..4898996 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain FHI_NMBU_11     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4893340..4903996
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GHT02_RS23585 (GHT02_23555) dcyD 4894220..4895206 (+) 987 WP_001128219.1 D-cysteine desulfhydrase -
  GHT02_RS23590 (GHT02_23560) tcyL 4895221..4895889 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  GHT02_RS23595 (GHT02_23565) tcyN 4895886..4896638 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  GHT02_RS23600 (GHT02_23570) sdiA 4896868..4897590 (+) 723 WP_001154276.1 transcriptional regulator SdiA -
  GHT02_RS23605 (GHT02_23575) yecF 4897657..4897881 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  GHT02_RS23610 (GHT02_23580) yecU 4897868..4898044 (-) 177 WP_000590347.1 protein YecU -
  GHT02_RS28030 - 4898127..4898198 (-) 72 Protein_4658 transcriptional regulator -
  GHT02_RS23615 (GHT02_23585) letA 4898340..4898996 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  GHT02_RS23620 (GHT02_23590) uvrC 4898993..4900825 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  GHT02_RS23625 (GHT02_23595) pgsA 4900882..4901430 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  GHT02_RS23645 (GHT02_23615) yecA 4902080..4902745 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=345501 GHT02_RS23615 WP_000611335.1 4898340..4898996(+) (letA) [Escherichia coli strain FHI_NMBU_11]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=345501 GHT02_RS23615 WP_000611335.1 4898340..4898996(+) (letA) [Escherichia coli strain FHI_NMBU_11]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486