Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   GFB63_RS08890 Genome accession   NZ_CP045596
Coordinates   1724019..1725863 (+) Length   614 a.a.
NCBI ID   WP_176693514.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain TK-P3A     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1719019..1730863
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GFB63_RS11185 - 1720084..1720257 (+) 174 Protein_1713 hypothetical protein -
  GFB63_RS08880 (GFB63_09130) prx 1721900..1722088 (+) 189 WP_003045927.1 hypothetical protein Regulator
  GFB63_RS08885 (GFB63_09135) - 1722269..1724017 (+) 1749 WP_003045929.1 type IA DNA topoisomerase -
  GFB63_RS08890 (GFB63_09140) clpE 1724019..1725863 (+) 1845 WP_176693514.1 AAA family ATPase Regulator
  GFB63_RS08895 (GFB63_09145) - 1725956..1726303 (+) 348 WP_000791789.1 TrbC/VirB2 family protein -
  GFB63_RS08900 (GFB63_09150) - 1726314..1727387 (+) 1074 WP_003045936.1 hypothetical protein -
  GFB63_RS08905 (GFB63_09155) - 1727407..1728189 (+) 783 WP_193838260.1 LPXTG cell wall anchor domain-containing protein -
  GFB63_RS08910 (GFB63_09160) - 1728317..1729321 (-) 1005 WP_193838261.1 IS5-like element ISSth7 family transposase -

Sequence

Protein


Download         Length: 614 a.a.        Molecular weight: 68915.87 Da        Isoelectric Point: 4.8635

>NTDB_id=345263 GFB63_RS08890 WP_176693514.1 1724019..1725863(+) (clpE) [Streptococcus thermophilus strain TK-P3A]
MDDELKTPYLDKYTDNLSAKVAKKSDDYQVYGRDKEVKAVIISLLRRTKNNPILVGEAGVGKTAIVEGLTLAIMRGQVPE
PLKRLTVRSLELSSLMSEEDGGFIAKFKKIIEEMVATRGRNLLFVDEFHTIVGAGSQDGQALDAGNVIKPVLARGDIQLI
GATTLDEFHDYVETDRALERRMQPVMVEEPTIPQAISIIDQAKIIYEKFHGIQISSEAVKQAVRLSVRYLTDRFLPDKAF
DLIDEAATIASAEGKDSITEEDIAQVLKDKTGIPVTTILKGDQERLDGLKEKLMNRVKGQEDAIDAIVDAVTIAQAGLQD
ENKPISSFMFLGPTGVGKTELSKALAEALFDDENAMIRFDMSEFKEKEDAAKLIGNRATKTKGQLTQAVKQKPYCVVLLD
EVEKADGEVLDLFLQVLDDGRLTDSSGRLISFKNTIVIMTTNIGAKKIINKWELKGSFQHLTERDRQQFEKSMISELETE
FRPEFLNRIENKLIFNLLEREIIEKIAEKNLSEIEDRMRRQNMTLSYEPSLIQYLSDVGTDVKNGARPLERLIKRKVLAP
ISAKSLSLDKSRQTYNIHLWVEGEAPDSQHRKDLRQIQLDVEGEIGEEVDALFS

Nucleotide


Download         Length: 1845 bp        

>NTDB_id=345263 GFB63_RS08890 WP_176693514.1 1724019..1725863(+) (clpE) [Streptococcus thermophilus strain TK-P3A]
GTGGACGATGAATTGAAGACCCCCTATCTTGATAAATACACTGATAATTTGTCAGCTAAGGTTGCTAAAAAATCAGATGA
TTACCAAGTTTATGGCCGTGATAAGGAAGTAAAAGCGGTCATTATCTCTCTTCTCAGACGAACTAAAAATAATCCTATCT
TGGTAGGAGAAGCTGGAGTTGGGAAAACAGCTATTGTGGAAGGCCTAACGCTTGCTATTATGCGTGGTCAAGTTCCTGAA
CCTTTAAAAAGGTTAACAGTTCGCTCTCTGGAACTCTCTAGCTTGATGAGTGAAGAAGATGGTGGCTTTATTGCCAAGTT
TAAGAAGATTATTGAAGAGATGGTTGCGACACGTGGCCGTAATCTTCTCTTTGTAGATGAATTTCATACTATCGTTGGTG
CAGGTAGCCAAGATGGTCAAGCCCTCGATGCAGGAAATGTGATTAAACCAGTTTTAGCACGTGGGGATATTCAGCTTATT
GGTGCGACTACCTTAGATGAGTTTCATGACTATGTAGAGACTGATAGAGCCTTGGAACGTCGGATGCAACCAGTCATGGT
AGAAGAGCCCACCATTCCACAAGCCATATCCATTATTGATCAGGCCAAAATAATTTATGAGAAATTTCATGGGATTCAAA
TTTCTTCTGAAGCTGTGAAACAAGCTGTACGTTTATCTGTTCGTTATCTAACAGATCGCTTTCTGCCAGACAAAGCTTTT
GATTTGATTGATGAAGCAGCAACCATTGCTTCAGCTGAAGGAAAAGACAGTATTACAGAAGAGGATATTGCCCAGGTCTT
GAAGGATAAAACTGGTATTCCTGTCACTACAATATTAAAAGGTGATCAGGAACGCTTAGATGGTCTGAAGGAAAAATTAA
TGAATCGTGTCAAGGGGCAAGAGGATGCTATTGATGCTATTGTGGATGCTGTCACTATTGCTCAAGCTGGATTGCAAGAT
GAGAATAAACCGATTTCGTCATTCATGTTCCTGGGCCCAACAGGTGTTGGTAAAACAGAGTTATCAAAGGCTTTAGCTGA
AGCGCTCTTTGATGATGAAAATGCTATGATTCGTTTTGATATGTCTGAGTTCAAAGAGAAAGAAGATGCAGCTAAACTGA
TTGGTAATCGTGCAACGAAAACAAAAGGGCAGCTGACACAGGCTGTAAAACAAAAGCCTTATTGCGTTGTATTACTAGAT
GAGGTTGAAAAGGCTGATGGTGAAGTTCTGGATCTTTTTCTTCAGGTGCTAGATGATGGTCGTTTAACAGATAGTTCAGG
ACGTTTGATTAGCTTCAAAAATACTATTGTCATAATGACCACTAATATTGGAGCCAAAAAGATTATCAATAAATGGGAGT
TGAAGGGGAGTTTCCAGCATTTAACAGAACGTGATAGGCAACAATTTGAGAAGTCAATGATTAGTGAACTTGAAACTGAG
TTTAGACCAGAGTTCCTTAATCGTATTGAAAATAAGCTTATCTTCAATCTTTTGGAACGAGAAATTATTGAAAAGATAGC
AGAAAAAAACTTGTCTGAAATTGAAGATAGAATGAGGCGTCAAAATATGACACTCTCATATGAGCCTAGTTTAATTCAGT
ATTTATCTGATGTTGGAACCGATGTAAAAAATGGCGCACGTCCCTTAGAGCGTTTGATTAAAAGAAAAGTTTTAGCCCCT
ATTTCAGCTAAAAGTCTTTCTTTAGATAAAAGTAGGCAAACCTACAATATTCATCTATGGGTTGAGGGAGAGGCACCAGA
TAGCCAACATCGAAAAGATTTGAGACAAATTCAGCTAGATGTTGAAGGAGAAATTGGAGAAGAAGTTGATGCTCTTTTCA
GCTGA

Domains

Predicted by InterProScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(323-490)

AAA lid domain (AAA_lid_9)

(192-268)

ATPase family associated with various cellular activities (AAA) (AAA)

(53-165)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(498-567)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae TIGR4

41.225

98.371

0.406
  clpE Streptococcus pneumoniae R6

41.06

98.371

0.404
  clpE Streptococcus pneumoniae D39

41.06

98.371

0.404
  clpE Streptococcus pneumoniae Rx1

41.06

98.371

0.404
  clpE Streptococcus mutans UA159

40.692

98.86

0.402
  clpC Lactococcus lactis subsp. cremoris KW2

40.23

99.186

0.399
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

39.005

100

0.396
  clpC Bacillus subtilis subsp. subtilis str. 168

38.611

100

0.389
  clpC Streptococcus pneumoniae Rx1

40.203

96.417

0.388
  clpC Streptococcus pneumoniae D39

40.203

96.417

0.388
  clpC Streptococcus pneumoniae TIGR4

40.203

96.417

0.388
  clpC Streptococcus thermophilus LMD-9

39.899

96.743

0.386
  clpC Streptococcus thermophilus LMG 18311

39.731

96.743

0.384
  clpC Streptococcus mutans UA159

39.43

97.068

0.383

Multiple sequence alignment