Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   ERW13_RS07835 Genome accession   NZ_CP035791
Coordinates   1491807..1492376 (-) Length   189 a.a.
NCBI ID   WP_000872882.1    Uniprot ID   A0A7U7EXA1
Organism   Staphylococcus aureus strain 592     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1486807..1497376
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ERW13_RS07790 - 1487282..1487890 (-) 609 WP_000020304.1 class I SAM-dependent methyltransferase -
  ERW13_RS07795 rplL 1488065..1488433 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  ERW13_RS07800 rplJ 1488476..1488976 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  ERW13_RS07810 rplA 1489247..1489939 (-) 693 WP_130163220.1 50S ribosomal protein L1 -
  ERW13_RS07815 rplK 1490147..1490569 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  ERW13_RS07820 nusG 1490750..1491298 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  ERW13_RS07825 secE 1491311..1491493 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  ERW13_RS07830 rpmG 1491549..1491692 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  ERW13_RS07835 sigH 1491807..1492376 (-) 570 WP_000872882.1 RNA polymerase sigma factor Regulator
  ERW13_RS07840 - 1492457..1492981 (-) 525 WP_000664737.1 NYN domain-containing protein -
  ERW13_RS07845 rlmB 1492981..1493727 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  ERW13_RS07850 - 1493735..1494139 (-) 405 WP_000370182.1 Mini-ribonuclease 3 -
  ERW13_RS07855 cysS 1494132..1495532 (-) 1401 WP_000631969.1 cysteine--tRNA ligase -
  ERW13_RS07860 cysE 1495516..1496163 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23044.91 Da        Isoelectric Point: 9.4170

>NTDB_id=344450 ERW13_RS07835 WP_000872882.1 1491807..1492376(-) (sigH) [Staphylococcus aureus strain 592]
MKYDLTTQDSTIKRNNSINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=344450 ERW13_RS07835 WP_000872882.1 1491807..1492376(-) (sigH) [Staphylococcus aureus strain 592]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATTCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

100

100

1
  sigH Staphylococcus aureus MW2

97.884

100

0.979

Multiple sequence alignment