Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ERW13_RS02275 Genome accession   NZ_CP035791
Coordinates   402466..403152 (+) Length   228 a.a.
NCBI ID   WP_001802022.1    Uniprot ID   A0A7U7EYP5
Organism   Staphylococcus aureus strain 592     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 397466..408152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ERW13_RS02240 yqeH 397993..399093 (+) 1101 WP_001280137.1 ribosome biogenesis GTPase YqeH -
  ERW13_RS02245 aroE 399107..399913 (+) 807 WP_000666757.1 shikimate dehydrogenase -
  ERW13_RS02250 yhbY 399917..400207 (+) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  ERW13_RS02255 nadD 400210..400779 (+) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  ERW13_RS02260 yqeK 400769..401353 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ERW13_RS02265 rsfS 401354..401707 (+) 354 WP_001088020.1 ribosome silencing factor -
  ERW13_RS02270 - 401710..402426 (+) 717 WP_000084830.1 class I SAM-dependent methyltransferase -
  ERW13_RS02275 comEA 402466..403152 (+) 687 WP_001802022.1 ComEA family DNA-binding protein Machinery gene
  ERW13_RS02280 - 403244..403705 (+) 462 WP_000439693.1 ComE operon protein 2 -
  ERW13_RS02285 comEC 403710..405911 (+) 2202 WP_001557362.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ERW13_RS02290 holA 405968..406942 (+) 975 WP_001282563.1 DNA polymerase III subunit delta -
  ERW13_RS02295 rpsT 406987..407238 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25900.65 Da        Isoelectric Point: 9.6751

>NTDB_id=344430 ERW13_RS02275 WP_001802022.1 402466..403152(+) (comEA) [Staphylococcus aureus strain 592]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=344430 ERW13_RS02275 WP_001802022.1 402466..403152(+) (comEA) [Staphylococcus aureus strain 592]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EYP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

100

100

1
  comEA Staphylococcus aureus MW2

97.368

100

0.974

Multiple sequence alignment