Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   GBF15_RS09450 Genome accession   NZ_CP045277
Coordinates   1964768..1965424 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain LAU-OXA     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1959768..1970424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GBF15_RS09415 dcyD 1960647..1961633 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  GBF15_RS09420 tcyL 1961648..1962316 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  GBF15_RS09425 tcyN 1962313..1963065 (+) 753 WP_001272990.1 L-cystine ABC transporter ATP-binding protein TcyN -
  GBF15_RS09430 sdiA 1963295..1964017 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  GBF15_RS09435 yecF 1964085..1964309 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  GBF15_RS09440 yecU 1964296..1964472 (-) 177 WP_001302050.1 protein YecU -
  GBF15_RS26195 - 1964510..1964626 (-) 117 WP_001302039.1 hypothetical protein -
  GBF15_RS09450 letA 1964768..1965424 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  GBF15_RS09455 uvrC 1965421..1967253 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  GBF15_RS09460 pgsA 1967310..1967858 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  GBF15_RS09480 yecA 1968508..1969173 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=344093 GBF15_RS09450 WP_000611328.1 1964768..1965424(+) (letA) [Escherichia coli strain LAU-OXA]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=344093 GBF15_RS09450 WP_000611328.1 1964768..1965424(+) (letA) [Escherichia coli strain LAU-OXA]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482