Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SDEG_RS08220 Genome accession   NC_012891
Coordinates   1615044..1616369 (-) Length   441 a.a.
NCBI ID   WP_003059901.1    Uniprot ID   A0AAE9QQW5
Organism   Streptococcus dysgalactiae subsp. equisimilis GGS_124     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1610044..1621369
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SDEG_RS08205 (SDEG_1680) - 1612630..1613649 (-) 1020 Protein_1577 IS30 family transposase -
  SDEG_RS08210 (SDEG_1681) raiA 1613779..1614327 (-) 549 WP_003061817.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  SDEG_RS11475 (SDEG_1682) - 1614407..1615072 (-) 666 WP_012767419.1 ComF family protein -
  SDEG_RS08220 (SDEG_1683) comFA/cflA 1615044..1616369 (-) 1326 WP_003059901.1 DEAD/DEAH box helicase Machinery gene
  SDEG_RS08225 (SDEG_1684) - 1616425..1617063 (+) 639 WP_003062333.1 YigZ family protein -
  SDEG_RS08230 (SDEG_1685) cysK 1617167..1618102 (+) 936 WP_012767420.1 cysteine synthase A -
  SDEG_RS08235 (SDEG_1686) - 1618255..1618614 (-) 360 WP_003056775.1 S1 RNA-binding domain-containing protein -
  SDEG_RS08240 (SDEG_1687) - 1618614..1620014 (-) 1401 WP_041789112.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SDEG_RS08245 (SDEG_1688) - 1620051..1620692 (-) 642 WP_014612503.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49225.41 Da        Isoelectric Point: 9.7796

>NTDB_id=34401 SDEG_RS08220 WP_003059901.1 1615044..1616369(-) (comFA/cflA) [Streptococcus dysgalactiae subsp. equisimilis GGS_124]
MEGIENSYGRLFLKHQLPKEVNHLAKTLESIVAIKGKVTCQRCHYQITAEARLPSGTYYCRFCLVFGRNQADRPLYYIPP
HPFPIANYLQWKGILTPYQESISNQLVKNVHAKKPTLVHAVTGAGKTEMIYGAIAAVVNAGGWVCLASPRVDVCIELANR
LKAAFSCRVTLLHADSEAYQRSPIIVATTHQLLTFYKAFDLLIIDEVDAFPFVNNHQLQYAAQQAAKEGASSIVLTATST
KELEEQVKSGELEKLTLARRFHGNPLILPKFIRSFGLLKKIHCQKLPRALVKSISQQRKTGCPLLIFLPIIAMAELVTEL
LKLAFPEEQIACVSSQSADRVKDIDAFRQGKKGILVTTTILERGVTFPGVDVFVLMAQHRGYSSQSLVQIAGRVGRSIER
PTGKVYFFHDGISQAMRNARKEIKEMNQKGYLNDMPPMSTI

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=34401 SDEG_RS08220 WP_003059901.1 1615044..1616369(-) (comFA/cflA) [Streptococcus dysgalactiae subsp. equisimilis GGS_124]
ATGGAAGGTATCGAAAACAGTTACGGTCGTTTATTTTTAAAACATCAATTGCCAAAAGAAGTAAATCATCTGGCAAAGAC
CTTGGAAAGTATAGTAGCCATAAAAGGTAAAGTCACTTGTCAACGCTGTCATTATCAGATAACCGCAGAAGCGAGATTAC
CAAGTGGCACTTACTACTGCCGCTTCTGTCTCGTTTTTGGCCGAAATCAAGCTGATAGGCCTCTTTATTATATACCTCCA
CATCCTTTTCCTATAGCCAATTATCTTCAATGGAAGGGGATATTAACGCCCTACCAAGAAAGTATTTCAAACCAATTAGT
CAAGAATGTTCATGCTAAAAAACCTACTTTAGTGCATGCTGTTACCGGAGCCGGCAAGACAGAGATGATTTATGGAGCCA
TAGCAGCAGTTGTTAATGCTGGAGGTTGGGTTTGTTTAGCCAGCCCAAGGGTCGATGTTTGTATAGAACTTGCTAATCGC
TTAAAAGCTGCTTTTTCTTGCCGGGTTACTCTTTTACATGCTGACTCAGAAGCTTATCAAAGAAGTCCTATTATAGTAGC
TACTACCCATCAATTACTGACCTTTTATAAGGCTTTTGATCTTTTAATCATTGATGAAGTTGATGCTTTTCCTTTTGTCA
ATAATCATCAACTACAATATGCAGCGCAGCAAGCCGCTAAAGAAGGCGCTAGTAGTATCGTATTGACCGCGACATCGACC
AAAGAACTGGAAGAGCAGGTCAAAAGTGGGGAACTAGAGAAGTTGACATTAGCTAGACGATTCCACGGTAATCCTTTGAT
TCTTCCGAAATTTATCAGGAGTTTTGGTCTATTAAAAAAAATTCACTGTCAAAAACTTCCTCGAGCTCTTGTTAAATCTA
TCAGTCAACAAAGGAAAACAGGATGTCCACTGCTAATTTTCCTTCCTATTATTGCCATGGCAGAATTAGTTACTGAATTA
TTAAAGTTAGCTTTTCCAGAGGAACAAATTGCCTGTGTCTCTAGCCAATCAGCTGACAGAGTTAAAGACATTGATGCCTT
TCGTCAAGGAAAGAAAGGTATTTTGGTGACCACCACAATATTGGAAAGGGGTGTTACTTTCCCAGGCGTGGATGTCTTTG
TGCTTATGGCACAGCATCGAGGATACAGTTCTCAAAGCTTGGTTCAAATCGCAGGTCGTGTGGGGAGATCTATCGAAAGG
CCAACAGGGAAGGTGTATTTCTTTCACGATGGGATTAGCCAAGCAATGCGCAATGCAAGAAAAGAAATTAAAGAAATGAA
TCAGAAAGGTTATTTGAATGATATGCCTCCTATGTCAACAATTTAG

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(99-244)

Helicase conserved C-terminal domain (Helicase_C)

(289-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae D39

53.538

96.145

0.515
  comFA/cflA Streptococcus pneumoniae R6

53.538

96.145

0.515
  comFA/cflA Streptococcus pneumoniae TIGR4

53.538

96.145

0.515
  comFA/cflA Streptococcus pneumoniae Rx1

53.538

96.145

0.515
  comFA/cflA Streptococcus mitis SK321

52.448

97.279

0.51
  comFA/cflA Streptococcus mitis NCTC 12261

52.083

97.959

0.51
  comFA Lactococcus lactis subsp. cremoris KW2

46.717

89.796

0.419
  comFA Latilactobacillus sakei subsp. sakei 23K

37.819

97.732

0.37

Multiple sequence alignment