Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   FSA31_RS05780 Genome accession   NZ_CP044492
Coordinates   1177351..1179138 (-) Length   595 a.a.
NCBI ID   WP_002284296.1    Uniprot ID   -
Organism   Streptococcus mutans strain T8     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1172351..1184138
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA31_RS05750 (FSA31_1136) - 1172828..1173631 (-) 804 WP_002284294.1 amidohydrolase family protein -
  FSA31_RS05755 (FSA31_1137) - 1173649..1173999 (-) 351 WP_002265574.1 nuclear transport factor 2 family protein -
  FSA31_RS05760 (FSA31_1138) - 1174090..1174392 (+) 303 WP_002265575.1 helix-turn-helix domain-containing protein -
  FSA31_RS05765 (FSA31_1139) - 1174521..1175108 (-) 588 WP_002274756.1 uracil-DNA glycosylase family protein -
  FSA31_RS05770 (FSA31_1140) pepV 1175181..1176587 (-) 1407 WP_002284295.1 dipeptidase PepV -
  FSA31_RS05775 (FSA31_1141) - 1176602..1177204 (-) 603 WP_002263202.1 nitroreductase family protein -
  FSA31_RS05780 (FSA31_1142) uvrC 1177351..1179138 (-) 1788 WP_002284296.1 excinuclease ABC subunit UvrC Machinery gene
  FSA31_RS05785 - 1179247..1180402 (+) 1156 Protein_1078 low temperature requirement protein A -
  FSA31_RS05790 (FSA31_1145) - 1180446..1181141 (-) 696 WP_002264091.1 YjjG family noncanonical pyrimidine nucleotidase -
  FSA31_RS05795 (FSA31_1146) - 1181220..1181516 (-) 297 WP_002284299.1 TetR/AcrR family transcriptional regulator -
  FSA31_RS05800 (FSA31_1147) eno 1181580..1182878 (-) 1299 WP_002263196.1 surface-displayed alpha-enolase -
  FSA31_RS05805 (FSA31_1149) - 1183274..1183915 (-) 642 WP_002265582.1 DUF4352 domain-containing protein -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68879.29 Da        Isoelectric Point: 9.3809

>NTDB_id=342802 FSA31_RS05780 WP_002284296.1 1177351..1179138(-) (uvrC) [Streptococcus mutans strain T8]
MNELIKHKLELLPDSPGCYIHKDKNGTIIYVGKAKNLKNRVRSYFHGSHNTKTELLVSEIEDFEYIVTGSNTEALLLEIN
LIQENKPKYNIRLKDDKSYPFIKITNEPYPRLLITRQVKKDGGLYFGPYPDSGAATEIKRLLDRLFPFKKCTNPANKVCF
YYHLGQCKAHTICQTDQTYWDSLKEDVKNFLNGRDDKIVNELRDKMTKASELMEFERAAEYRDLIEGIGLLRTKQRVMNQ
DMQDRDIFGYYVDKGWMCVQVFFIRQGKLIQRDVNMFPYYNESEEDFLTYVGQFYQDNRHFIPKEIFIPRDIDETLVKAV
VNTKIIKPQRGEKKQLVNLATKNARVSLQQKFDLLEKDIRKTHGAIENIGDLLNIPKPVRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVMRDGLTPPDLIIIDGGQGQVNIARDVIENKLGLDIPIAGLQ
KNDKHQTHELLFGDPLEVIPLPRNSEEFFLLQRIQDEVHRFAITFHRQLRGKNTFSSKLDGIAGLGPKRKQLLMKHFKNL
PNIQKASLDDIINCGIPKNVAENIQESLQEKREKG

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=342802 FSA31_RS05780 WP_002284296.1 1177351..1179138(-) (uvrC) [Streptococcus mutans strain T8]
ATGAACGAACTGATTAAACATAAGCTGGAATTGCTGCCAGATAGTCCTGGCTGTTATATTCACAAGGATAAAAACGGCAC
CATTATCTATGTCGGTAAGGCCAAGAACTTAAAAAACCGTGTACGCAGCTATTTTCACGGCAGCCATAATACCAAGACAG
AATTGTTGGTTTCGGAAATTGAGGATTTTGAATACATTGTTACTGGGTCAAATACAGAAGCTTTACTTCTTGAGATTAAT
CTCATTCAGGAAAATAAGCCCAAGTACAATATCAGACTCAAAGATGATAAGTCTTATCCTTTTATTAAAATTACCAATGA
ACCTTATCCGCGTTTATTGATTACCCGTCAGGTGAAAAAGGATGGCGGTCTTTATTTTGGTCCCTACCCTGATTCGGGAG
CTGCTACTGAAATTAAGCGACTTTTAGATCGTCTCTTTCCCTTTAAAAAATGCACCAACCCAGCCAACAAGGTCTGTTTT
TATTATCATCTCGGGCAATGCAAGGCGCATACCATTTGTCAGACCGACCAAACCTATTGGGATAGTCTTAAAGAAGATGT
GAAAAACTTTCTCAATGGCAGGGACGATAAGATTGTCAATGAACTGCGCGATAAAATGACCAAAGCTTCTGAGCTCATGG
AATTTGAACGTGCAGCTGAATACCGAGATCTTATTGAGGGCATTGGTCTGTTGCGAACCAAGCAGCGCGTCATGAATCAG
GATATGCAGGATCGTGATATTTTTGGTTATTATGTTGATAAAGGCTGGATGTGTGTGCAGGTTTTCTTTATTCGTCAGGG
AAAGCTTATTCAGCGCGATGTCAATATGTTTCCTTATTACAATGAGTCTGAGGAAGATTTTCTGACCTATGTAGGACAGT
TCTATCAGGATAACCGTCACTTTATTCCAAAGGAGATTTTTATTCCTAGAGATATTGATGAAACTTTGGTTAAAGCGGTG
GTCAATACTAAGATTATCAAACCGCAGCGCGGCGAGAAGAAGCAGTTAGTCAATCTGGCAACGAAAAATGCTCGTGTTAG
CCTGCAGCAGAAATTTGATCTCTTGGAAAAAGATATTCGAAAAACGCATGGTGCGATTGAAAATATTGGAGATTTACTTA
ATATTCCTAAGCCAGTGCGCATTGAAGCCTTTGATAATTCCAACATTCAAGGAACCAGTCCTGTTGCAGCTATGGTTGTT
TTTGTGGACGGCAAGCCAAGTAAGAAGGATTATCGTAAATTTAAAATCAAAACCGTTATCGGACCTGATGACTATGCCAG
CATGCGTGAGGTTATTTATCGCAGATATAGCCGTGTCATGCGAGATGGACTGACACCACCAGACCTGATTATTATTGATG
GGGGACAAGGTCAGGTTAATATAGCGCGTGACGTTATCGAAAATAAATTGGGACTCGATATTCCTATCGCTGGTTTGCAA
AAAAATGATAAGCACCAAACCCATGAGCTGCTCTTTGGTGATCCGCTGGAAGTGATTCCTCTGCCTAGAAATTCAGAAGA
GTTCTTTCTCTTGCAGCGCATTCAAGACGAAGTGCATCGCTTTGCCATTACATTTCATAGGCAGCTGCGCGGTAAAAACA
CCTTCTCATCAAAGCTGGACGGTATTGCAGGGCTCGGCCCTAAGCGCAAGCAATTGCTGATGAAACACTTTAAGAATCTT
CCTAATATTCAAAAGGCCAGCCTAGATGATATTATCAACTGCGGCATTCCAAAAAATGTCGCAGAGAACATTCAGGAGAG
CTTGCAAGAGAAAAGAGAAAAAGGTTAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(196-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

77.234

99.664

0.77
  uvrC Streptococcus pneumoniae R6

76.897

99.664

0.766
  uvrC Streptococcus pneumoniae D39

76.897

99.664

0.766