Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   FSA31_RS02345 Genome accession   NZ_CP044492
Coordinates   474462..475103 (+) Length   213 a.a.
NCBI ID   WP_002263036.1    Uniprot ID   -
Organism   Streptococcus mutans strain T8     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 469462..480103
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA31_RS02325 (FSA31_0457) - 469739..470482 (+) 744 WP_002284356.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  FSA31_RS02330 (FSA31_0458) pknB 470479..472329 (+) 1851 WP_002263039.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FSA31_RS02335 (FSA31_0460) liaF 472773..473468 (+) 696 WP_002263038.1 cell wall-active antibiotics response protein LiaF -
  FSA31_RS02340 (FSA31_0461) - 473465..474469 (+) 1005 WP_002280714.1 sensor histidine kinase -
  FSA31_RS02345 (FSA31_0462) vraR 474462..475103 (+) 642 WP_002263036.1 response regulator transcription factor Regulator
  FSA31_RS02350 (FSA31_0463) - 475147..476562 (+) 1416 WP_002284357.1 Cof-type HAD-IIB family hydrolase -
  FSA31_RS02355 (FSA31_0464) - 476546..476932 (+) 387 WP_002263034.1 S1 RNA-binding domain-containing protein -
  FSA31_RS02360 (FSA31_0465) - 477011..477787 (-) 777 WP_002280716.1 glycyl-radical enzyme activating protein -
  FSA31_RS02365 (FSA31_0466) - 477918..478664 (+) 747 WP_002284358.1 DeoR/GlpR family DNA-binding transcription regulator -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23824.40 Da        Isoelectric Point: 4.8864

>NTDB_id=342764 FSA31_RS02345 WP_002263036.1 474462..475103(+) (vraR) [Streptococcus mutans strain T8]
MSKTKVILVDDHEMVRLGLKSFLNLQDNVEVIGEASNGRQGIDLALKLKPDVVVMDLVMPEMDGVEATLELLKDWKEAKI
LVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVAKGDLAIETEVDKKIKDHHNNPDLHEDLTARERDILALLA
KGYDNQTIADELFISLKTVKTHVSNILSKLQVDDRTQAVVYAFQHHLVPQDEN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=342764 FSA31_RS02345 WP_002263036.1 474462..475103(+) (vraR) [Streptococcus mutans strain T8]
ATGAGTAAAACAAAAGTTATACTGGTTGATGATCATGAAATGGTTCGATTGGGTTTGAAAAGTTTTCTTAATTTACAAGA
TAATGTAGAAGTTATCGGTGAGGCTAGCAATGGCCGTCAAGGTATTGACTTGGCTTTAAAATTAAAACCAGACGTTGTTG
TCATGGACTTGGTTATGCCAGAAATGGATGGTGTAGAAGCCACTCTTGAACTTCTAAAAGATTGGAAAGAAGCCAAAATT
CTAGTTTTAACCAGTTATTTAGATAACGAAAAAATTTATCCTGTCATTGAAGCAGGTGCTAAAGGTTATATGTTGAAAAC
TTCCAGCGCAGCTGAAATTTTGAATGCCATTCAAAAAGTAGCTAAGGGAGATTTAGCGATTGAAACAGAAGTTGATAAGA
AAATCAAGGATCATCATAATAATCCTGATTTGCATGAAGATTTAACAGCGCGTGAACGAGACATTTTGGCTTTACTTGCT
AAGGGTTATGATAACCAAACGATTGCTGATGAGCTTTTCATTTCTTTGAAGACTGTCAAAACACATGTTTCTAATATCTT
ATCGAAATTACAAGTTGATGATCGGACCCAAGCCGTTGTCTATGCTTTTCAGCATCATTTAGTGCCACAGGACGAAAATT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.22

96.244

0.493
  degU Bacillus subtilis subsp. subtilis str. 168

35.398

100

0.376