Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HeN100_RS10730 Genome accession   NZ_CP044443
Coordinates   1859485..1860141 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain HeN100     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1854485..1865141
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HeN100_RS10700 (HeN100_10930) dcyD 1855364..1856350 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  HeN100_RS10705 (HeN100_10935) tcyL 1856365..1857033 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  HeN100_RS10710 (HeN100_10940) tcyN 1857030..1857782 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  HeN100_RS10715 (HeN100_10945) sdiA 1858012..1858734 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  HeN100_RS10720 (HeN100_10950) yecF 1858802..1859026 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  HeN100_RS10725 (HeN100_10955) yecU 1859013..1859189 (-) 177 WP_000590344.1 protein YecU -
  HeN100_RS24390 (HeN100_10960) - 1859227..1859343 (-) 117 Protein_1765 transcriptional regulator -
  HeN100_RS10730 (HeN100_10965) letA 1859485..1860141 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  HeN100_RS10735 (HeN100_10970) uvrC 1860138..1861970 (+) 1833 WP_112922410.1 excinuclease ABC subunit UvrC Machinery gene
  HeN100_RS10740 (HeN100_10975) pgsA 1862027..1862575 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HeN100_RS10760 (HeN100_11000) - 1863271..1864011 (-) 741 WP_112922411.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=342550 HeN100_RS10730 WP_000611335.1 1859485..1860141(+) (letA) [Escherichia coli strain HeN100]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=342550 HeN100_RS10730 WP_000611335.1 1859485..1860141(+) (letA) [Escherichia coli strain HeN100]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486