Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   ETT45_RS01375 Genome accession   NZ_CP035454
Coordinates   252610..253680 (+) Length   356 a.a.
NCBI ID   WP_002992231.1    Uniprot ID   A0A5S4TWS5
Organism   Streptococcus pyogenes strain emm54     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 247610..258680
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT45_RS01360 (ETT45_01360) amiA 248138..250108 (+) 1971 WP_002992224.1 peptide ABC transporter substrate-binding protein Regulator
  ETT45_RS01365 (ETT45_01365) amiC 250173..251675 (+) 1503 WP_002992227.1 ABC transporter permease Regulator
  ETT45_RS01370 (ETT45_01370) amiD 251675..252601 (+) 927 WP_002986004.1 oligopeptide ABC transporter permease OppC Regulator
  ETT45_RS01375 (ETT45_01375) amiE 252610..253680 (+) 1071 WP_002992231.1 ABC transporter ATP-binding protein Regulator
  ETT45_RS01380 (ETT45_01380) amiF 253673..254596 (+) 924 WP_136129581.1 ABC transporter ATP-binding protein Regulator
  ETT45_RS09130 (ETT45_01385) - 254634..254723 (-) 90 WP_109821088.1 IS3 family transposase -
  ETT45_RS08770 - 254744..254989 (-) 246 WP_186789748.1 transposase -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 39680.74 Da        Isoelectric Point: 5.4774

>NTDB_id=342449 ETT45_RS01375 WP_002992231.1 252610..253680(+) (amiE) [Streptococcus pyogenes strain emm54]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSNAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=342449 ETT45_RS01375 WP_002992231.1 252610..253680(+) (amiE) [Streptococcus pyogenes strain emm54]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTAATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(29-187)

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-299)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5S4TWS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus salivarius strain HSISS4

76.667

100

0.775
  amiE Streptococcus thermophilus LMG 18311

75.556

100

0.764
  amiE Streptococcus thermophilus LMD-9

75.556

100

0.764
  oppD Streptococcus mutans UA159

56.677

94.663

0.537

Multiple sequence alignment