Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   F7O57_RS14860 Genome accession   NZ_CP044403
Coordinates   3004008..3004664 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain NMBU-W10C18     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2999008..3009664
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F7O57_RS14830 (F7O57_15155) yecA 3000259..3000924 (-) 666 WP_000847881.1 UPF0149 family protein YecA -
  F7O57_RS14850 (F7O57_15175) pgsA 3001574..3002122 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  F7O57_RS14855 (F7O57_15180) uvrC 3002179..3004011 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  F7O57_RS14860 (F7O57_15185) letA 3004008..3004664 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  F7O57_RS14865 (F7O57_15190) yecU 3004960..3005136 (+) 177 WP_000590347.1 protein YecU -
  F7O57_RS14870 (F7O57_15195) yecF 3005123..3005347 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  F7O57_RS14875 (F7O57_15200) sdiA 3005414..3006136 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  F7O57_RS14880 (F7O57_15205) tcyN 3006366..3007118 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  F7O57_RS14885 (F7O57_15210) tcyL 3007115..3007783 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  F7O57_RS14890 (F7O57_15215) dcyD 3007798..3008784 (-) 987 WP_020232905.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=342391 F7O57_RS14860 WP_000611328.1 3004008..3004664(-) (letA) [Escherichia coli strain NMBU-W10C18]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=342391 F7O57_RS14860 WP_000611328.1 3004008..3004664(-) (letA) [Escherichia coli strain NMBU-W10C18]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment