Detailed information NTG0342346

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ETT47_RS02295
• Genome accession: NZ_CP035452
• Coordinates: 419523..420524 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain emm123
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 414523..425524

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT47_RS02270 (ETT47_02265)	-	415197..415880 (-)	684	WP_023078761.1	DUF969 domain-containing protein	-
ETT47_RS02275 (ETT47_02270)	-	416091..417017 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
ETT47_RS02280 (ETT47_02275)	-	417162..417539 (-)	378	WP_063631793.1	VOC family protein	-
ETT47_RS02285 (ETT47_02280)	-	417550..418215 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
ETT47_RS02290 (ETT47_02285)	-	418264..419349 (-)	1086	WP_136099107.1	aminopeptidase P family protein	-
ETT47_RS02295 (ETT47_02290)	ccpA	419523..420524 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
ETT47_RS02300 (ETT47_02295)	-	420655..421653 (+)	999	WP_030127183.1	glycosyltransferase family 4 protein	-
ETT47_RS02305 (ETT47_02300)	-	421655..422989 (+)	1335	WP_030127184.1	glycosyltransferase family 4 protein	-
ETT47_RS02310 (ETT47_02305)	thrS	423411..425354 (+)	1944	WP_136099108.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=342346 ETT47_RS02295 WP_002985680.1 419523..420524(+) (ccpA) [Streptococcus pyogenes strain emm123]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=342346 ETT47_RS02295 WP_002985680.1 419523..420524(+) (ccpA) [Streptococcus pyogenes strain emm123]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559