Detailed information NTG0342195

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ETT50_RS05775
• Genome accession: NZ_CP035449
• Coordinates: 1104067..1105296 (-)
• Length: 409 a.a.
• NCBI ID: WP_032464958.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm56
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1099067..1110296

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT50_RS05755 (ETT50_05755)	rpiA	1099349..1100032 (-)	684	WP_009881270.1	ribose-5-phosphate isomerase RpiA	-
ETT50_RS05760 (ETT50_05760)	-	1100410..1102509 (+)	2100	WP_032464959.1	AAA family ATPase	-
ETT50_RS05765 (ETT50_05765)	-	1102567..1103310 (-)	744	WP_002984942.1	hypothetical protein	-
ETT50_RS05770 (ETT50_05770)	yihA	1103458..1104057 (-)	600	WP_011184414.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ETT50_RS05775 (ETT50_05775)	clpX	1104067..1105296 (-)	1230	WP_032464958.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ETT50_RS05780 (ETT50_05780)	-	1105426..1105596 (-)	171	WP_002990165.1	hypothetical protein	-
ETT50_RS05785 (ETT50_05785)	-	1105616..1106113 (-)	498	WP_002984955.1	dihydrofolate reductase	-
ETT50_RS05790 (ETT50_05790)	-	1106193..1107032 (-)	840	WP_011017679.1	thymidylate synthase	-
ETT50_RS05795 (ETT50_05795)	-	1107241..1108416 (+)	1176	WP_032464957.1	hydroxymethylglutaryl-CoA synthase	-
ETT50_RS05800 (ETT50_05800)	-	1108403..1109680 (+)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45033.57 Da
• Isoelectric Point: 4.6616

>NTDB_id=342195 ETT50_RS05775 WP_032464958.1 1104067..1105296(-) (clpX) [Streptococcus pyogenes strain emm56]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKTSDLIRI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=342195 ETT50_RS05775 WP_032464958.1 1104067..1105296(-) (clpX) [Streptococcus pyogenes strain emm56]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGTCGTTTACCAGTTGTGGCAGCCCTTGAACAACTTAAAACATCAGATTTGATTCGAATC
TTAACAGAGCCAAGGAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575