Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   ETT56_RS02705 Genome accession   NZ_CP035443
Coordinates   522330..523655 (+) Length   441 a.a.
NCBI ID   WP_063633007.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm58     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 517330..528655
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT56_RS02680 (ETT56_02680) - 518100..518741 (+) 642 WP_002983671.1 response regulator transcription factor -
  ETT56_RS02685 (ETT56_02685) - 518778..520178 (+) 1401 WP_023610569.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ETT56_RS02690 (ETT56_02690) - 520178..520555 (+) 378 WP_023610575.1 S1 RNA-binding domain-containing protein -
  ETT56_RS02695 (ETT56_02695) cysK 520573..521514 (-) 942 WP_011888673.1 cysteine synthase A -
  ETT56_RS02700 (ETT56_02700) - 521642..522274 (-) 633 WP_032465870.1 YigZ family protein -
  ETT56_RS02705 (ETT56_02705) comFA/cflA 522330..523655 (+) 1326 WP_063633007.1 DEAD/DEAH box helicase Machinery gene
  ETT56_RS02710 (ETT56_02710) - 523627..524292 (+) 666 WP_002983685.1 ComF family protein -
  ETT56_RS02715 (ETT56_02715) raiA 524372..524920 (+) 549 WP_002988974.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49786.32 Da        Isoelectric Point: 10.0009

>NTDB_id=341857 ETT56_RS02705 WP_063633007.1 522330..523655(+) (comFA/cflA) [Streptococcus pyogenes strain emm58]
MESIENSYGRLLLESQLPDSAKQLAQPLKSVVILRGKMICQRCHYQLDEEARLPSGAYYCRFCLVFGRNQSDKLLYAIPP
MHFPKGNYLVWGGQLTAYQEMISQQLLINMQNQKTTLVHAVTGAGKTEMIYAAIEAVINTGGWVCIVSPRVDVCVEVATR
LSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQLHYAASQALKEGGAKILLTATST
RTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFNLFKMIHRQKLPPKILKYLKKQRKTGYPLLIFLPTIIMAESVTAI
LKDLLPAEQIACVSSQSQNRKEDITAFRQGKKTILITTTILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAGRVGRSIDR
PDGTLYFFHEGISKAMPLARKEIKEMNYKGYSHDLSTMSTN

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=341857 ETT56_RS02705 WP_063633007.1 522330..523655(+) (comFA/cflA) [Streptococcus pyogenes strain emm58]
ATGGAGTCTATTGAAAATAGTTATGGACGGTTGTTGCTAGAAAGCCAGTTACCAGATTCAGCAAAGCAGCTTGCTCAACC
TTTAAAAAGTGTAGTAATATTGAGAGGAAAAATGATTTGTCAACGTTGTCACTATCAGCTTGATGAAGAAGCACGATTGC
CAAGTGGAGCCTATTATTGCCGATTTTGTCTTGTCTTTGGACGAAATCAATCAGATAAATTGCTCTATGCTATCCCACCT
ATGCATTTTCCAAAAGGTAATTATCTGGTTTGGGGCGGTCAACTAACTGCTTATCAAGAGATGATTTCCCAACAATTATT
AATCAATATGCAAAATCAAAAAACAACATTAGTTCATGCTGTAACTGGTGCAGGAAAAACAGAAATGATTTATGCTGCGA
TTGAGGCGGTAATTAACACAGGTGGCTGGGTTTGCATTGTCAGCCCAAGAGTAGATGTTTGTGTAGAGGTGGCTACTCGT
TTATCCCAAGCCTTCTCCTGCAGCATCTGTTTAATGCACGCAGAGTCTCTTCCTTATCAAAGAGCTCCTATTATAGTAGC
CACAACGCATCAGCTGCTAAAATTTCACAAGGCTTTTGATCTCTTAATTATTGATGAAGTAGACGCATTCCCTTTTGTAA
ATAATATTCAACTTCATTATGCTGCAAGTCAGGCTTTAAAAGAAGGTGGCGCAAAGATTTTATTAACTGCAACTTCAACT
AGAACTTTAGAAAGAAAGGTAAACAAGGGAGAAGTAGTCAAGCTGACATTGGCGAGACGCTTTCATAATAGGCCATTAGT
TATTCCAAAATTTATAAGAAGTTTTAATCTATTTAAAATGATACATCGGCAAAAACTTCCTCCTAAAATTTTAAAATACT
TAAAAAAACAAAGAAAAACAGGCTATCCCCTTTTAATTTTTCTACCCACTATTATAATGGCAGAATCTGTTACAGCAATC
TTAAAAGACTTATTGCCCGCCGAACAAATAGCTTGTGTTTCTAGTCAATCACAAAACAGGAAAGAAGATATCACAGCTTT
TCGTCAAGGGAAAAAAACGATTTTAATTACAACAACAATTTTAGAAAGGGGTGTGACATTTCCCCAAATTGATGTTTTTG
TTCTTGGGTCTCATCATCGTGTCTATAGTTCCCAAAGTCTTGTTCAAATTGCTGGACGAGTTGGAAGATCTATAGACAGA
CCAGACGGAACGTTATATTTCTTTCATGAAGGTATCAGTAAAGCAATGCCACTAGCAAGAAAAGAGATTAAAGAAATGAA
TTATAAAGGGTATTCGCATGATCTGTCTACTATGTCAACAAATTAG

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(98-244)

Helicase conserved C-terminal domain (Helicase_C)

(289-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

53.699

95.011

0.51
  comFA/cflA Streptococcus pneumoniae D39

53.699

95.011

0.51
  comFA/cflA Streptococcus pneumoniae R6

53.699

95.011

0.51
  comFA/cflA Streptococcus pneumoniae TIGR4

53.699

95.011

0.51
  comFA/cflA Streptococcus mitis NCTC 12261

52.37

95.692

0.501
  comFA/cflA Streptococcus mitis SK321

51.659

95.692

0.494
  comFA Lactococcus lactis subsp. cremoris KW2

47.222

89.796

0.424
  comFA Latilactobacillus sakei subsp. sakei 23K

39.08

98.639

0.385

Multiple sequence alignment