Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   ETT60_RS08660 Genome accession   NZ_CP035439
Coordinates   1713583..1714296 (+) Length   237 a.a.
NCBI ID   WP_129284221.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm77     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1714575..1733578 1713583..1714296 flank 279


Gene organization within MGE regions


Location: 1713583..1733578
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT60_RS08660 (ETT60_08650) treR 1713583..1714296 (+) 714 WP_129284221.1 trehalose operon repressor Regulator
  ETT60_RS08670 (ETT60_08660) - 1714575..1714814 (-) 240 WP_229293985.1 helix-turn-helix domain-containing protein -
  ETT60_RS08675 (ETT60_08665) - 1715092..1715949 (+) 858 WP_129284222.1 VOC family protein -
  ETT60_RS08680 (ETT60_08670) yaaA 1715991..1716722 (+) 732 WP_012561068.1 peroxide stress protein YaaA -
  ETT60_RS08685 (ETT60_08675) nrdG 1716896..1717510 (-) 615 WP_002982219.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  ETT60_RS08690 (ETT60_08680) - 1717510..1718019 (-) 510 WP_129284223.1 GNAT family N-acetyltransferase -
  ETT60_RS08695 (ETT60_08685) - 1718028..1718963 (-) 936 WP_129284224.1 Gfo/Idh/MocA family protein -
  ETT60_RS09220 - 1718992..1719138 (-) 147 WP_023610752.1 hypothetical protein -
  ETT60_RS08700 (ETT60_08690) nrdD 1719320..1721518 (-) 2199 WP_002992831.1 anaerobic ribonucleoside-triphosphate reductase -
  ETT60_RS08705 (ETT60_08695) - 1721615..1723174 (-) 1560 WP_115354331.1 DUF2079 domain-containing protein -
  ETT60_RS08710 (ETT60_08700) - 1723587..1723892 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  ETT60_RS08715 (ETT60_08705) ruvX 1723904..1724323 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  ETT60_RS08720 (ETT60_08710) - 1724320..1724589 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  ETT60_RS08725 (ETT60_08715) spx 1724703..1725101 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  ETT60_RS08730 (ETT60_08720) recA 1725392..1726528 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  ETT60_RS08735 (ETT60_08725) cinA 1726617..1727888 (-) 1272 WP_030126182.1 competence/damage-inducible protein A Machinery gene
  ETT60_RS08740 (ETT60_08730) - 1727957..1728517 (-) 561 WP_063812052.1 DNA-3-methyladenine glycosylase I -
  ETT60_RS08745 (ETT60_08735) ruvA 1728527..1729123 (-) 597 WP_011285268.1 Holliday junction branch migration protein RuvA -
  ETT60_RS08750 (ETT60_08740) - 1729125..1730345 (-) 1221 WP_136114721.1 MFS transporter -
  ETT60_RS08755 (ETT60_08745) mutL 1730356..1732338 (-) 1983 WP_032467454.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27574.75 Da        Isoelectric Point: 9.6226

>NTDB_id=341665 ETT60_RS08660 WP_129284221.1 1713583..1714296(+) (treR) [Streptococcus pyogenes strain emm77]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIKHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIITREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=341665 ETT60_RS08660 WP_129284221.1 1713583..1714296(+) (treR) [Streptococcus pyogenes strain emm77]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAAACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACACGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATAACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTCTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTGCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterproScan.

UTRA domain (UTRA)

(91-227)

Bacterial regulatory proteins, gntR family (GntR)

(3-66)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

68.376

98.734

0.675

Multiple sequence alignment