Detailed information NTG0341639

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ETT60_RS02395
• Genome accession: NZ_CP035439
• Coordinates: 433806..434807 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain emm77
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 428806..439807

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT60_RS02370 (ETT60_02365)	-	429480..430163 (-)	684	WP_012560521.1	DUF969 domain-containing protein	-
ETT60_RS02375 (ETT60_02370)	-	430374..431300 (-)	927	WP_030126781.1	glycosyltransferase family 2 protein	-
ETT60_RS02380 (ETT60_02375)	-	431445..431822 (-)	378	WP_002985686.1	VOC family protein	-
ETT60_RS02385 (ETT60_02380)	-	431833..432498 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
ETT60_RS02390 (ETT60_02385)	-	432547..433632 (-)	1086	WP_030126780.1	aminopeptidase P family protein	-
ETT60_RS02395 (ETT60_02390)	ccpA	433806..434807 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
ETT60_RS02400 (ETT60_02395)	-	434938..435936 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
ETT60_RS02405 (ETT60_02400)	-	435938..437272 (+)	1335	WP_030126779.1	glycosyltransferase family 4 protein	-
ETT60_RS02410 (ETT60_02405)	thrS	437694..439637 (+)	1944	WP_030126778.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=341639 ETT60_RS02395 WP_002985680.1 433806..434807(+) (ccpA) [Streptococcus pyogenes strain emm77]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=341639 ETT60_RS02395 WP_002985680.1 433806..434807(+) (ccpA) [Streptococcus pyogenes strain emm77]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAATGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559