Detailed information NTG0341596

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ETT61_RS05555
• Genome accession: NZ_CP035438
• Coordinates: 1040054..1041283 (-)
• Length: 409 a.a.
• NCBI ID: WP_136020246.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm22.8
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1035054..1046283

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT61_RS05535 (ETT61_05525)	rpiA	1035336..1036019 (-)	684	WP_002994002.1	ribose-5-phosphate isomerase RpiA	-
ETT61_RS05540 (ETT61_05530)	-	1036397..1038496 (+)	2100	WP_136020247.1	AAA family ATPase	-
ETT61_RS05545 (ETT61_05535)	-	1038554..1039297 (-)	744	WP_002984942.1	hypothetical protein	-
ETT61_RS05550 (ETT61_05540)	yihA	1039445..1040044 (-)	600	WP_011184414.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ETT61_RS05555 (ETT61_05545)	clpX	1040054..1041283 (-)	1230	WP_136020246.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ETT61_RS05560 (ETT61_05550)	-	1041413..1041583 (-)	171	WP_002990165.1	hypothetical protein	-
ETT61_RS05565 (ETT61_05555)	-	1041603..1042100 (-)	498	WP_002984955.1	dihydrofolate reductase	-
ETT61_RS05570 (ETT61_05560)	-	1042180..1043019 (-)	840	WP_011017679.1	thymidylate synthase	-
ETT61_RS05575 (ETT61_05565)	-	1043228..1044403 (+)	1176	WP_023609855.1	hydroxymethylglutaryl-CoA synthase	-
ETT61_RS05580 (ETT61_05570)	-	1044390..1045667 (+)	1278	WP_020833420.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45035.45 Da
• Isoelectric Point: 4.5458

>NTDB_id=341596 ETT61_RS05555 WP_136020246.1 1040054..1041283(-) (clpX) [Streptococcus pyogenes strain emm22.8]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKDAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=341596 ETT61_RS05555 WP_136020246.1 1040054..1041283(-) (clpX) [Streptococcus pyogenes strain emm22.8]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTATACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCTAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGATGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-390)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575