Detailed information NTG0341491

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ETT63_RS05595
• Genome accession: NZ_CP035436
• Coordinates: 1085051..1086280 (-)
• Length: 409 a.a.
• NCBI ID: WP_009880296.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm89.14
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1080051..1091280

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT63_RS05575 (ETT63_05575)	rpiA	1080336..1081019 (-)	684	WP_136116769.1	ribose-5-phosphate isomerase RpiA	-
ETT63_RS05580 (ETT63_05580)	-	1081397..1083493 (+)	2097	WP_136267092.1	AAA family ATPase	-
ETT63_RS05585 (ETT63_05585)	-	1083551..1084294 (-)	744	WP_002984942.1	hypothetical protein	-
ETT63_RS05590 (ETT63_05590)	yihA	1084442..1085041 (-)	600	WP_011184414.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ETT63_RS05595 (ETT63_05595)	clpX	1085051..1086280 (-)	1230	WP_009880296.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ETT63_RS05600 (ETT63_05600)	-	1086410..1086580 (-)	171	WP_002990165.1	hypothetical protein	-
ETT63_RS05605 (ETT63_05605)	-	1086600..1087097 (-)	498	WP_136047827.1	dihydrofolate reductase	-
ETT63_RS05610 (ETT63_05610)	-	1087177..1088016 (-)	840	WP_002990167.1	thymidylate synthase	-
ETT63_RS05615 (ETT63_05615)	-	1088225..1089400 (+)	1176	WP_136026179.1	hydroxymethylglutaryl-CoA synthase	-
ETT63_RS05620 (ETT63_05620)	-	1089387..1090664 (+)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45020.57 Da
• Isoelectric Point: 4.6616

>NTDB_id=341491 ETT63_RS05595 WP_009880296.1 1085051..1086280(-) (clpX) [Streptococcus pyogenes strain emm89.14]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKTSDLIRI
LTEPRNALVKQYQALLSYDGVELEFDKAALEAIATKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=341491 ETT63_RS05595 WP_009880296.1 1085051..1086280(-) (clpX) [Streptococcus pyogenes strain emm89.14]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTTAAAACATCAGATTTGATTCGAATC
TTAACAGAGCCAAGGAATGCTCTTGTCAAGCAATATCAGGCCCTTCTTTCCTATGATGGGGTAGAATTAGAATTTGATAA
AGCAGCTCTTGAAGCTATCGCAACTAAAGCGATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CAATGCTTGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575