Detailed information NTG0341392

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ETT65_RS07365
• Genome accession: NZ_CP035434
• Coordinates: 1449818..1450819 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain emm75.1
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1444818..1455819

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT65_RS07350 (ETT65_07345)	thrS	1444988..1446931 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
ETT65_RS07355 (ETT65_07350)	-	1447353..1448687 (-)	1335	WP_002985676.1	glycosyltransferase family 4 protein	-
ETT65_RS07360 (ETT65_07355)	-	1448689..1449687 (-)	999	WP_136075656.1	glycosyltransferase family 4 protein	-
ETT65_RS07365 (ETT65_07360)	ccpA	1449818..1450819 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
ETT65_RS07370 (ETT65_07365)	-	1450993..1452078 (+)	1086	WP_136097816.1	aminopeptidase P family protein	-
ETT65_RS07375 (ETT65_07370)	-	1452127..1452792 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
ETT65_RS07380 (ETT65_07375)	-	1452803..1453180 (+)	378	WP_002985686.1	VOC family protein	-
ETT65_RS07385 (ETT65_07380)	-	1453325..1454251 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
ETT65_RS07390 (ETT65_07385)	-	1454462..1455145 (+)	684	WP_002990714.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=341392 ETT65_RS07365 WP_002985680.1 1449818..1450819(-) (ccpA) [Streptococcus pyogenes strain emm75.1]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=341392 ETT65_RS07365 WP_002985680.1 1449818..1450819(-) (ccpA) [Streptococcus pyogenes strain emm75.1]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAATGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559