Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   F4V25_RS01065 Genome accession   NZ_CP044171
Coordinates   120758..122560 (-) Length   600 a.a.
NCBI ID   WP_012006742.1    Uniprot ID   A8FMV1
Organism   Campylobacter jejuni strain AR-0413     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 115758..127560
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F4V25_RS01040 - 115887..117086 (+) 1200 WP_057098364.1 MFS transporter -
  F4V25_RS01045 ciaC 117142..117462 (+) 321 WP_002866237.1 invasion antigen CiaC -
  F4V25_RS01050 hemE 117642..118664 (+) 1023 WP_057098365.1 uroporphyrinogen decarboxylase -
  F4V25_RS01055 - 118661..119563 (+) 903 WP_002866239.1 radical SAM protein -
  F4V25_RS01060 - 119560..120756 (-) 1197 WP_012006741.1 hypothetical protein -
  F4V25_RS01065 uvrC 120758..122560 (-) 1803 WP_012006742.1 excinuclease ABC subunit UvrC Machinery gene
  F4V25_RS01070 - 122553..123047 (-) 495 WP_002866244.1 hypothetical protein -
  F4V25_RS01075 guaA 123186..124721 (+) 1536 WP_002866245.1 glutamine-hydrolyzing GMP synthase -
  F4V25_RS01080 - 124807..126267 (+) 1461 WP_002866246.1 hypothetical protein -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69716.76 Da        Isoelectric Point: 9.3105

>NTDB_id=341385 F4V25_RS01065 WP_012006742.1 120758..122560(-) (uvrC) [Campylobacter jejuni strain AR-0413]
MTKENLENELKTLPNSAGVYQYFNQEGKLLYVGKAKNLKNRVKSYFAFTPNLHANPRNSLRIQKMIEETVHLEFITTNSE
ADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFEEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYPLKQK
ASCKSPCIFYQISRCLAPCDKRISREKYLEILDEAMHALLNPSILIKNLEKQMLVLAQNENYEEAAKVRDQIVTIKDLEV
KVEIDIAKLEDFEVFALAFENSMLSTLRFVVQNGKIISVNSKITPIKNDIQWDKNEIYKQLILENFSMDIPLLANVIYVY
EEFEDRMLLEEILSQRFDKKISIKIPKIGEKRRICDLAFQNALLNIEKEQKNHDFTIQKELKSYFELENLPNDIEIFDNS
HLQGVANVGAMVTYSANSWDKSKYRKFHLKHKNDYDQMREVLMRRALDFDKIPPPDLWLIDGGKALLDLAKEIIVSSGAN
VDILAISKEKIDAKAHRAKGGARDKIHSLKGEFSLSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLNSSKLVNLGLS
SGVIQKLLAYYGNFESIYKADFKDLAMLVGKKVAQKIKEN

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=341385 F4V25_RS01065 WP_012006742.1 120758..122560(-) (uvrC) [Campylobacter jejuni strain AR-0413]
TTGACTAAAGAGAATTTAGAAAATGAGTTAAAAACTCTTCCTAATAGTGCTGGAGTGTATCAATATTTTAATCAAGAAGG
AAAGCTTTTATATGTAGGTAAGGCTAAAAATCTTAAAAATCGTGTCAAATCTTATTTCGCTTTTACTCCAAATTTACATG
CAAACCCAAGAAATTCTTTAAGAATTCAAAAAATGATTGAAGAAACAGTGCATTTGGAATTTATCACTACTAATTCAGAA
GCCGATGCTTTGATTTTGGAAAATTCTTTTATCAAACAACTGCATCCAAAATATAATATTTTACTAAGAGATGATAAAAC
TTATCCTTATATTTATGTGGATTTTGAAGAAGAATTTCCACGCTTTGAGATCACTAGAAAATTAGTAAAAAAAAGCAAAA
TTAAATATTTTGGCCCTTTTTTTAAAGGCGCTAGAGAGCTTTTAGATGCGCTTTATTTATACTATCCTTTAAAGCAAAAA
GCAAGTTGTAAATCCCCTTGTATTTTTTATCAAATTTCTCGTTGTCTTGCGCCTTGTGATAAACGCATTAGCAGGGAAAA
ATACCTTGAAATTTTAGATGAGGCTATGCACGCGCTTTTAAATCCTAGTATTTTAATAAAAAATTTAGAAAAACAAATGC
TTGTTTTAGCACAGAATGAAAATTATGAAGAAGCAGCTAAAGTAAGAGATCAGATTGTAACGATTAAGGATTTAGAAGTT
AAGGTTGAAATAGATATTGCAAAATTAGAAGATTTTGAAGTATTTGCTTTAGCTTTTGAAAATTCCATGCTTTCAACCTT
GCGTTTTGTAGTGCAAAATGGAAAAATTATCAGTGTAAATTCTAAGATTACTCCTATAAAAAATGATATACAATGGGATA
AAAATGAAATTTATAAGCAACTGATTTTAGAAAATTTTAGCATGGATATTCCTTTGCTTGCAAATGTTATTTATGTTTAT
GAAGAATTTGAAGATAGAATGCTTTTAGAAGAAATTTTAAGCCAAAGGTTTGATAAAAAAATCAGTATTAAAATCCCTAA
AATAGGAGAAAAAAGAAGAATTTGTGATTTGGCTTTTCAAAATGCCCTTTTAAATATAGAAAAAGAGCAAAAAAATCATG
ATTTTACTATACAAAAAGAATTAAAGTCTTATTTTGAGCTTGAAAATTTACCAAATGATATAGAAATTTTTGATAATTCT
CATTTGCAAGGCGTGGCAAATGTTGGAGCTATGGTAACTTATAGTGCAAATTCTTGGGATAAGTCAAAATATCGCAAATT
TCATTTAAAACATAAAAATGATTATGATCAAATGCGTGAAGTTTTAATGCGTAGGGCTTTGGACTTTGATAAAATACCCC
CTCCTGATTTATGGCTTATAGATGGAGGCAAGGCTTTGCTTGATTTGGCTAAAGAAATCATTGTAAGTAGTGGGGCAAAT
GTCGATATTTTAGCTATTTCAAAAGAAAAAATCGATGCAAAAGCACATAGGGCTAAAGGAGGTGCTAGAGATAAAATTCA
TTCCTTAAAAGGAGAATTTAGCCTAAGTATTAACGATAAAAAACTACAATTCTTACAGAAATTAAGAGATGAAGCGCATC
GTTTTGCTATCAGCTTTCATCAAAATACTAAGAAAAAACAGGACTTGAATAGTTCTAAGCTTGTAAATTTAGGACTTAGT
TCAGGGGTTATACAAAAACTTTTAGCGTATTATGGAAATTTTGAATCTATATATAAGGCTGATTTTAAAGATCTTGCAAT
GCTTGTAGGCAAGAAAGTGGCACAAAAGATAAAGGAAAATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-236)

GIY-YIG catalytic domain (GIY-YIG)

(18-99)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(383-537)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8FMV1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

45.96

99

0.455

Multiple sequence alignment