Detailed information NTG0341383

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: F4V25_RS00945
• Genome accession: NZ_CP044171
• Coordinates: 98937..99602 (-)
• Length: 221 a.a.
• NCBI ID: WP_002853205.1
• Uniprot ID: Q0P933
• Organism: Campylobacter jejuni strain AR-0413
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 93937..104602

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F4V25_RS00930	groES	95793..96053 (+)	261	WP_002825273.1	co-chaperone GroES	-
F4V25_RS00935	groL	96074..97711 (+)	1638	WP_002859291.1	chaperonin GroEL	-
F4V25_RS00940	dccS	97754..98944 (-)	1191	WP_002866221.1	two-component system sensor histidine kinase DccS	-
F4V25_RS00945	ciaR	98937..99602 (-)	666	WP_002853205.1	two-component system response regulator DccR	Regulator
F4V25_RS00950	-	99750..100349 (+)	600	WP_002866222.1	bacteriohemerythrin	-
F4V25_RS09165	-	100360..100599 (+)	240	Protein_103	ribbon-helix-helix domain-containing protein	-
F4V25_RS00965	-	100988..102235 (-)	1248	WP_002853920.1	ArsS family sensor histidine kinase	-
F4V25_RS00970	-	102232..102906 (-)	675	WP_002777451.1	response regulator transcription factor	-
F4V25_RS00975	htrA	102982..104400 (-)	1419	WP_002853541.1	serine protease HtrA	-

Sequence

Protein

• Length: 221 a.a.
• Molecular weight: 25633.32 Da
• Isoelectric Point: 4.6834

>NTDB_id=341383 F4V25_RS00945 WP_002853205.1 98937..99602(-) (ciaR) [Campylobacter jejuni strain AR-0413]
MAAKILLLEDDLSLSEIIEEFLNDEGYEVFLCDNAQEALDMAYERYFDLWILDVKVPLGDGFSLLKELRKSGKQTPAIFM
TSLNTTNDLKQGFDAGCDDYIKKPFELAELSIRVKALLKRAFSHKNEDFEDLGDGFRFEFTTQILYHNNKALTLPSKEIK
LLSLLLKNKNNFLSTERIFEELWDYDEEPSELSLRAYVKNLRKILGKEKIINQRGRGYCYG

Nucleotide

• Length: 666 bp

>NTDB_id=341383 F4V25_RS00945 WP_002853205.1 98937..99602(-) (ciaR) [Campylobacter jejuni strain AR-0413]
ATGGCTGCTAAAATTTTACTTTTAGAAGATGATTTGAGCTTGAGTGAGATCATTGAAGAGTTTTTAAACGATGAAGGATA
TGAAGTATTTTTATGCGATAATGCACAAGAAGCTTTAGATATGGCTTATGAAAGATATTTTGATCTTTGGATTTTAGATG
TAAAAGTTCCTTTAGGAGATGGATTTTCATTACTTAAAGAATTAAGAAAAAGCGGAAAGCAAACTCCAGCAATTTTCATG
ACTTCTTTAAACACAACAAACGATTTAAAACAAGGCTTTGACGCAGGTTGTGATGATTATATAAAAAAACCTTTTGAACT
TGCCGAGTTATCTATCAGGGTTAAAGCTTTGCTTAAAAGAGCTTTTTCACATAAAAATGAAGATTTTGAAGATTTAGGAG
ATGGATTTAGATTTGAATTTACTACACAAATTCTTTACCATAATAATAAAGCCTTGACTTTACCGAGTAAAGAAATTAAG
CTTTTGTCTTTATTACTTAAAAATAAAAACAACTTTTTAAGCACAGAGAGAATTTTTGAAGAACTCTGGGATTATGATGA
GGAGCCTAGTGAGCTAAGTTTAAGAGCTTATGTAAAAAATTTACGTAAAATTTTAGGAAAAGAAAAAATTATAAATCAAA
GAGGCAGGGGATATTGCTATGGCTAA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (5-114)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (150-219)

3D structure

• AlphaFold DB: Q0P933

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	36.364	99.548	0.362
ciaR	Streptococcus pneumoniae D39	36.364	99.548	0.362
ciaR	Streptococcus pneumoniae R6	36.364	99.548	0.362
ciaR	Streptococcus pneumoniae TIGR4	36.364	99.548	0.362