Detailed information    

insolico Bioinformatically predicted

Overview

Name   comS   Type   Regulator
Locus tag   ETT66_RS09280 Genome accession   NZ_CP035433
Coordinates   51586..51681 (+) Length   31 a.a.
NCBI ID   WP_198462994.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm65     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 46586..56681
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT66_RS00275 (ETT66_00275) - 47434..48546 (+) 1113 WP_168665103.1 DUF262 domain-containing protein -
  ETT66_RS00280 (ETT66_00280) - 48550..49158 (+) 609 WP_032464127.1 hypothetical protein -
  ETT66_RS00285 (ETT66_00285) purB 49168..50460 (+) 1293 WP_136286590.1 adenylosuccinate lyase -
  ETT66_RS00290 (ETT66_00290) comR 50591..51502 (+) 912 WP_002986681.1 transcriptional regulator Rgg4/ComR Regulator
  ETT66_RS09280 comS 51586..51681 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  ETT66_RS00295 (ETT66_00295) ruvB 51728..52726 (+) 999 WP_136286592.1 Holliday junction branch migration DNA helicase RuvB -
  ETT66_RS00300 (ETT66_00300) - 52864..53301 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  ETT66_RS00305 (ETT66_00305) - 53324..53725 (+) 402 WP_002986671.1 MORN repeat-containing protein -
  ETT66_RS00310 (ETT66_00310) - 53722..55497 (+) 1776 WP_136286594.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 31 a.a.        Molecular weight: 3857.66 Da        Isoelectric Point: 10.0436

>NTDB_id=341349 ETT66_RS09280 WP_198462994.1 51586..51681(+) (comS) [Streptococcus pyogenes strain emm65]
MLKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 96 bp        

>NTDB_id=341349 ETT66_RS09280 WP_198462994.1 51586..51681(+) (comS) [Streptococcus pyogenes strain emm65]
ATGTTAAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGCTGTTGA
CTGGTGGCGATTATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

100

100

1
  comS Streptococcus pyogenes MGAS315

45.161

100

0.452

Multiple sequence alignment