Detailed information NTG0341338

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ETT66_RS07050
• Genome accession: NZ_CP035433
• Coordinates: 1411080..1412081 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain emm65
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1406080..1417081

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT66_RS07035 (ETT66_07035)	thrS	1406250..1408193 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
ETT66_RS07040 (ETT66_07040)	-	1408615..1409949 (-)	1335	WP_136018800.1	glycosyltransferase family 4 protein	-
ETT66_RS07045 (ETT66_07045)	-	1409951..1410949 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
ETT66_RS07050 (ETT66_07050)	ccpA	1411080..1412081 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
ETT66_RS07055 (ETT66_07055)	-	1412255..1413340 (+)	1086	WP_002985682.1	aminopeptidase P family protein	-
ETT66_RS07060 (ETT66_07060)	-	1413389..1414054 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
ETT66_RS07065 (ETT66_07065)	-	1414065..1414442 (+)	378	WP_020904973.1	VOC family protein	-
ETT66_RS07070 (ETT66_07070)	-	1414587..1415513 (+)	927	WP_136271384.1	glycosyltransferase family 2 protein	-
ETT66_RS07075 (ETT66_07075)	-	1415724..1416407 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=341338 ETT66_RS07050 WP_002985680.1 1411080..1412081(-) (ccpA) [Streptococcus pyogenes strain emm65]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=341338 ETT66_RS07050 WP_002985680.1 1411080..1412081(-) (ccpA) [Streptococcus pyogenes strain emm65]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAATGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTACGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559