Detailed information NTG0341170

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ETT69_RS04100
• Genome accession: NZ_CP035430
• Coordinates: 772257..773486 (+)
• Length: 409 a.a.
• NCBI ID: WP_009880296.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm55
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 767257..778486

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT69_RS04075 (ETT69_04065)	-	767873..769150 (-)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-
ETT69_RS04080 (ETT69_04070)	-	769137..770312 (-)	1176	WP_023609855.1	hydroxymethylglutaryl-CoA synthase	-
ETT69_RS04085 (ETT69_04075)	-	770521..771360 (+)	840	WP_011017679.1	thymidylate synthase	-
ETT69_RS04090 (ETT69_04080)	-	771440..771937 (+)	498	WP_002984955.1	dihydrofolate reductase	-
ETT69_RS04095 (ETT69_04085)	-	771957..772127 (+)	171	WP_002990165.1	hypothetical protein	-
ETT69_RS04100 (ETT69_04090)	clpX	772257..773486 (+)	1230	WP_009880296.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ETT69_RS04105 (ETT69_04095)	yihA	773496..774095 (+)	600	WP_002990160.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ETT69_RS04110 (ETT69_04100)	-	774243..774986 (+)	744	WP_002984942.1	hypothetical protein	-
ETT69_RS04115 (ETT69_04105)	-	775044..777143 (-)	2100	WP_136019319.1	AAA family ATPase	-
ETT69_RS04120 (ETT69_04110)	rpiA	777521..778204 (+)	684	WP_136019320.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45020.57 Da
• Isoelectric Point: 4.6616

>NTDB_id=341170 ETT69_RS04100 WP_009880296.1 772257..773486(+) (clpX) [Streptococcus pyogenes strain emm55]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKTSDLIRI
LTEPRNALVKQYQALLSYDGVELEFDKAALEAIATKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=341170 ETT69_RS04100 WP_009880296.1 772257..773486(+) (clpX) [Streptococcus pyogenes strain emm55]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTTAAAACATCAGATTTGATTCGAATC
TTAACAGAGCCAAGGAATGCTCTTGTCAAGCAATATCAGGCCCTTCTTTCCTATGATGGGGTTGAATTAGAATTTGATAA
AGCAGCTCTTGAAGCTATCGCAACTAAAGCGATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CAATGCTTGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575