Detailed information NTG0341061

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ETT71_RS03930
• Genome accession: NZ_CP035428
• Coordinates: 753327..754556 (+)
• Length: 409 a.a.
• NCBI ID: WP_136038267.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emmSTG866.1
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 748327..759556

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT71_RS03905 (ETT71_03900)	-	748943..750220 (-)	1278	WP_136093347.1	hydroxymethylglutaryl-CoA reductase, degradative	-
ETT71_RS03910 (ETT71_03905)	-	750207..751382 (-)	1176	WP_032464957.1	hydroxymethylglutaryl-CoA synthase	-
ETT71_RS03915 (ETT71_03910)	-	751591..752430 (+)	840	WP_011017679.1	thymidylate synthase	-
ETT71_RS03920 (ETT71_03915)	-	752510..753007 (+)	498	WP_002984955.1	dihydrofolate reductase	-
ETT71_RS03925 (ETT71_03920)	-	753027..753197 (+)	171	WP_002990165.1	hypothetical protein	-
ETT71_RS03930 (ETT71_03925)	clpX	753327..754556 (+)	1230	WP_136038267.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ETT71_RS03935 (ETT71_03930)	yihA	754566..755165 (+)	600	WP_002984945.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ETT71_RS03940 (ETT71_03935)	-	755313..756056 (+)	744	WP_002984942.1	hypothetical protein	-
ETT71_RS03945 (ETT71_03940)	-	756114..758213 (-)	2100	WP_136106881.1	AAA family ATPase	-
ETT71_RS03950 (ETT71_03945)	rpiA	758591..759274 (+)	684	WP_020905094.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45091.60 Da
• Isoelectric Point: 4.6281

>NTDB_id=341061 ETT71_RS03930 WP_136038267.1 753327..754556(+) (clpX) [Streptococcus pyogenes strain emmSTG866.1]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKTSDLIRI
LTEPRNALVKQYQALLSYDGVELEFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=341061 ETT71_RS03930 WP_136038267.1 753327..754556(+) (clpX) [Streptococcus pyogenes strain emmSTG866.1]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGCCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTTAAAACATCAGATTTGATTCGAATC
TTAACAGAGCCAAGGAATGCTCTTGTCAAGCAATATCAGGCCCTTCTTTCCTATGATGGGGTTGAATTAGAATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATCGAAGAAA
CGATGTTAGACATCATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	89.242	100	0.892
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575