Detailed information NTG0340950

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ETT73_RS03725
• Genome accession: NZ_CP035426
• Coordinates: 711284..712513 (+)
• Length: 409 a.a.
• NCBI ID: WP_136276734.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm57
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 706284..717513

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT73_RS03700 (ETT73_03695)	-	706900..708177 (-)	1278	WP_002984963.1	hydroxymethylglutaryl-CoA reductase, degradative	-
ETT73_RS03705 (ETT73_03700)	-	708164..709339 (-)	1176	WP_021299369.1	hydroxymethylglutaryl-CoA synthase	-
ETT73_RS03710 (ETT73_03705)	-	709548..710387 (+)	840	WP_136105076.1	thymidylate synthase	-
ETT73_RS03715 (ETT73_03710)	-	710467..710964 (+)	498	WP_136276735.1	dihydrofolate reductase	-
ETT73_RS03725 (ETT73_03720)	clpX	711284..712513 (+)	1230	WP_136276734.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ETT73_RS03730 (ETT73_03725)	yihA	712523..713122 (+)	600	WP_002984945.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ETT73_RS03735 (ETT73_03730)	-	713270..714013 (+)	744	WP_002984942.1	hypothetical protein	-
ETT73_RS03740 (ETT73_03735)	-	714071..716170 (-)	2100	WP_010922175.1	AAA family ATPase	-
ETT73_RS03745 (ETT73_03740)	rpiA	716548..717231 (+)	684	WP_021733827.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45007.44 Da
• Isoelectric Point: 4.5775

>NTDB_id=340950 ETT73_RS03725 WP_136276734.1 711284..712513(+) (clpX) [Streptococcus pyogenes strain emm57]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELSEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=340950 ETT73_RS03725 WP_136276734.1 711284..712513(+) (clpX) [Streptococcus pyogenes strain emm57]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGTCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCTAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATCGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCTCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATCGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.753	100	0.888
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575