Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   FOB62_RS10130 Genome accession   NZ_CP044102
Coordinates   2039059..2040843 (+) Length   594 a.a.
NCBI ID   WP_014612322.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_654     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2034059..2045843
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOB62_RS10100 (FOB62_10105) - 2034370..2035044 (+) 675 WP_003058422.1 HAD family phosphatase -
  FOB62_RS10105 (FOB62_10110) - 2035060..2035626 (+) 567 WP_138128089.1 sugar O-acetyltransferase -
  FOB62_RS10110 (FOB62_10115) - 2035844..2036515 (+) 672 WP_015017085.1 DUF1524 domain-containing protein -
  FOB62_RS10115 (FOB62_10120) - 2036563..2037270 (+) 708 WP_003054308.1 YjjG family noncanonical pyrimidine nucleotidase -
  FOB62_RS10120 (FOB62_10125) - 2037348..2038724 (+) 1377 WP_014612324.1 NAD-dependent succinate-semialdehyde dehydrogenase -
  FOB62_RS10125 (FOB62_10130) - 2038780..2038929 (+) 150 WP_003054304.1 hypothetical protein -
  FOB62_RS10130 (FOB62_10135) uvrC 2039059..2040843 (+) 1785 WP_014612322.1 excinuclease ABC subunit UvrC Machinery gene
  FOB62_RS11465 - 2040905..2042554 (-) 1650 Protein_1960 thiamine pyrophosphate-dependent enzyme -
  FOB62_RS10155 (FOB62_10160) - 2042867..2043469 (+) 603 WP_003054310.1 nitroreductase family protein -
  FOB62_RS10160 (FOB62_10165) pepV 2043647..2045056 (+) 1410 WP_014612321.1 dipeptidase PepV -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68024.67 Da        Isoelectric Point: 9.3251

>NTDB_id=340627 FOB62_RS10130 WP_014612322.1 2039059..2040843(+) (uvrC) [Streptococcus dysgalactiae strain FDAARGOS_654]
MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNTEALLLEIN
LIQENMPKYNIKLKDDKSYPFIKITNETFPRLLITRQIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPVNKVCF
YYHLGQCCAHTICHTDKAYWDGLVEDVKHFLNGKDDKIIDGLRAKMLAASEEMAFERAAEYRDLISGIAIMRTKQRVMSK
DLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNEAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAI
VPTKIIKPQRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIDNLGYLLGIDKPVRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVAGPDDYASMREVIFRRYSRVKHEGLVAPDLIIIDGGIGQVNAAREVIEDRLGLTIPIAGLQ
KNDKHQTHELLFGKPLEVVPLPRNSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDKIPGLGPKRKQILLKHFKTM
TAIAAASPDEIHSLGIPRAVASAVHQHLTDSQQS

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=340627 FOB62_RS10130 WP_014612322.1 2039059..2040843(+) (uvrC) [Streptococcus dysgalactiae strain FDAARGOS_654]
ATGAATGAACTGATTAAACACAAGCTAGAACTCTTGCCAGATAGTCCTGGTTGCTACTTGCATAAGGACAAAGAGGGAAC
TATTATCTATGTAGGTAAAGCTAAGAATTTGAAGAACCGAGTGCGGTCTTATTTTCGTGGTAGCCATGATACCAAAACAG
AATTATTGGTGTCTGAGATTGCTGATTTTGAATTTATTGTGACCGAATCAAATACTGAGGCTCTCTTGCTTGAAATCAAC
TTGATTCAAGAAAACATGCCCAAGTATAATATCAAGCTCAAAGATGACAAGTCTTATCCTTTTATCAAAATCACCAATGA
GACCTTTCCTCGCTTGCTTATTACGAGACAGATTAAGAAAAATGACGGTCTATATTTCGGGCCCTATCCAGATTCGTACA
CCGCTAACGAAGTGAAAAAATTGCTGGATCGCATTTTTCCCTTTAAGAAATGTAAAAACCCTGTCAATAAGGTCTGTTTT
TATTACCATTTAGGACAGTGTTGTGCTCATACTATCTGCCATACAGATAAGGCTTATTGGGATGGTCTGGTAGAGGATGT
CAAACACTTTTTGAATGGTAAGGATGACAAGATTATTGATGGGCTGCGGGCAAAAATGTTAGCAGCTTCTGAAGAAATGG
CATTTGAACGTGCCGCTGAATATCGAGATTTGATTTCAGGTATTGCCATCATGCGCACCAAGCAGCGGGTGATGAGTAAG
GACTTGCAAGACAGAGATATTTTTGGCTACTTTGTTGACAAGGGCTGGATGTGCGTACAGGTTTTCTTTGTCCGTCAAGG
GAAATTAATTCAGCGGGATGTTAACCTTTTTCCTTACTATAACGAGGCAGAAGAAGATTTTTTAACCTATATGGGGCAGT
TTTATCAAGATAAACAGCATTTTATCCCCAAAGAAGTCTTTATTCCAGAAGCTATTGACGAAGAACTAGTAGCGGCCATT
GTGCCAACTAAAATCATCAAGCCTCAACGGGGTGAGAAAAAACAATTGGTGGCTTTGGCGACCAAGAATGCACGTGTTAG
CCTTCAGCAGAAATTTGATTTGTTGGAAAAAGATATTAAGAAAACTAGCGGTGCCATTGACAATCTAGGCTACTTGTTAG
GAATTGACAAGCCAGTCCGGATTGAGGCTTTTGATAATTCCAACATTCAAGGGACAAGCCCCGTAGCGGCTATGGTTGTT
TTTGTTGACGGGAAACCTAGTAAGAAAGATTATCGTAAATTTAAGATTAAAACAGTGGCGGGCCCAGATGATTATGCCAG
CATGAGGGAAGTGATTTTTCGAAGGTATAGCCGCGTTAAACATGAAGGATTGGTTGCTCCTGATTTAATCATCATTGATG
GTGGGATAGGGCAAGTCAATGCGGCCAGAGAAGTGATTGAAGACCGACTAGGTTTAACGATTCCTATTGCGGGCTTGCAA
AAAAATGATAAGCACCAGACCCATGAATTGCTCTTTGGAAAGCCACTCGAGGTAGTCCCCTTACCCCGTAATTCAGAAGA
ATTTTTCCTCTTGCATCGCATCCAAGATGAGGTGCACCGCTTTGCGATTACTTTCCACCGACAGGTTCGCAGTAAAAATT
CATTCTCTTCGAAATTGGATAAGATTCCAGGACTAGGTCCGAAGCGCAAGCAGATACTGCTTAAACATTTTAAAACCATG
ACAGCCATTGCGGCAGCTAGTCCAGATGAGATTCATTCGTTAGGGATTCCTAGGGCAGTGGCATCAGCTGTCCATCAGCA
TCTGACAGACAGTCAGCAAAGTTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(196-227)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(373-523)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

75.722

99.158

0.751
  uvrC Streptococcus pneumoniae R6

75.382

99.158

0.747
  uvrC Streptococcus pneumoniae D39

75.382

99.158

0.747