Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   SGPB_RS00625 Genome accession   NC_015600
Coordinates   97172..97465 (+) Length   97 a.a.
NCBI ID   WP_080543606.1    Uniprot ID   -
Organism   Streptococcus pasteurianus ATCC 43144     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 92172..102465
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGPB_RS00600 (SGPB_0085) - 94168..94530 (+) 363 WP_003062916.1 DUF1033 family protein -
  SGPB_RS00605 (SGPB_0086) comGA 94601..95542 (+) 942 WP_003062917.1 competence type IV pilus ATPase ComGA Machinery gene
  SGPB_RS00610 (SGPB_0087) comGB 95466..96509 (+) 1044 WP_003062919.1 competence type IV pilus assembly protein ComGB Machinery gene
  SGPB_RS00615 (SGPB_0088) comGC 96509..96803 (+) 295 Protein_87 competence type IV pilus major pilin ComGC -
  SGPB_RS00620 (SGPB_0089) comGD 96787..97218 (+) 432 WP_003062922.1 competence type IV pilus minor pilin ComGD Machinery gene
  SGPB_RS00625 (SGPB_0090) comGE 97172..97465 (+) 294 WP_080543606.1 competence type IV pilus minor pilin ComGE Machinery gene
  SGPB_RS00630 (SGPB_0091) comGF 97449..97886 (+) 438 WP_041974065.1 competence type IV pilus minor pilin ComGF Machinery gene
  SGPB_RS00635 (SGPB_0092) comGG 97858..98190 (+) 333 WP_003062925.1 competence type IV pilus minor pilin ComGG Machinery gene
  SGPB_RS00640 (SGPB_0093) comGH 98245..99216 (+) 972 WP_003062926.1 class I SAM-dependent methyltransferase Machinery gene
  SGPB_RS00645 (SGPB_0094) - 99254..100453 (+) 1200 WP_003062927.1 acetate kinase -
  SGPB_RS00650 (SGPB_0095) - 100614..100814 (+) 201 WP_013851401.1 helix-turn-helix transcriptional regulator -
  SGPB_RS00655 (SGPB_0096) - 100824..101054 (+) 231 WP_013851402.1 hypothetical protein -
  SGPB_RS00660 (SGPB_0097) - 101045..101497 (+) 453 WP_003062930.1 hypothetical protein -
  SGPB_RS00665 (SGPB_0098) - 101509..102147 (+) 639 WP_003062931.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11069.10 Da        Isoelectric Point: 8.4757

>NTDB_id=34051 SGPB_RS00625 WP_080543606.1 97172..97465(+) (comGE) [Streptococcus pasteurianus ATCC 43144]
MVNIKRQKLKAYILLESLIALGLLAMITSIVLGEIDKNRQFMQESLRQQEVLNVATMAVQTGQNHLKMNGIEVEIIKKDG
EVYVYEAKTEILHVKKD

Nucleotide


Download         Length: 294 bp        

>NTDB_id=34051 SGPB_RS00625 WP_080543606.1 97172..97465(+) (comGE) [Streptococcus pasteurianus ATCC 43144]
GTGGTAAATATAAAAAGACAGAAACTAAAAGCTTACATACTCCTTGAAAGCTTGATAGCACTAGGATTGTTAGCGATGAT
TACGAGTATTGTTTTAGGGGAAATTGATAAAAATAGGCAGTTTATGCAAGAAAGTTTACGGCAGCAGGAAGTTCTTAATG
TGGCAACAATGGCTGTGCAAACAGGGCAAAATCATTTGAAGATGAATGGTATTGAGGTTGAGATTATCAAAAAAGATGGA
GAGGTCTATGTTTATGAGGCGAAAACGGAAATATTACATGTTAAAAAAGACTAG

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

46.875

98.969

0.464
  comGE Streptococcus mutans UA159

46.875

98.969

0.464
  comGE/cglE Streptococcus mitis SK321

40.426

96.907

0.392
  comGE/cglE Streptococcus pneumoniae Rx1

40.426

96.907

0.392
  comGE/cglE Streptococcus pneumoniae D39

40.426

96.907

0.392
  comGE/cglE Streptococcus pneumoniae R6

40.426

96.907

0.392
  comGE/cglE Streptococcus pneumoniae TIGR4

40.426

96.907

0.392
  comGE/cglE Streptococcus mitis NCTC 12261

39.362

96.907

0.381

Multiple sequence alignment